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research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque
Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.
research Synthesis and Structure–Activity Studies of Side-Chain Derivatized Arylhydantoins for Investigation as Androgen Receptor Radioligands
The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.
research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque
Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
research Clinical Updates in Hair
Most treatments for hair loss in 1997 were not effective for most people, and maintaining hair growth was difficult.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands
Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.
research Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance
Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.
research Development of Radioiodinated Nonsteroidal Androgen Receptor Ligands for SPECT Imaging of Prostate Cancer
Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.
research Persistent Escalation of Alcohol Consumption by Mice Exposed to Brief Episodes of Social Defeat Stress: Suppression by CRF-R1 Antagonism
Blocking CRF-R1 can reduce alcohol intake in stressed mice.
research Sex Hormones and Related Compounds, Including Hormonal Contraceptives
Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.
research Generation of iPS Cells from Human Hair Follicle Dermal Papilla Cells
Researchers made stem cells from human hair follicle cells with higher efficiency than from skin cells.
research Skin Tissue-Engineering Constructs and Stem Cells Application for the Creation of Skin Equivalents
The review says that stem cells are beneficial for making skin replacements.
research Safety and Tolerability of Antiepileptic Drugs in Women with Epilepsy: Literature Review and Own Data
Some epilepsy drugs can cause reproductive and cosmetic side effects in women and affect pregnancy, but most women still have healthy babies.
research The Value of Genetic and Non-Genetic Factors in the Emergence and Development of Androgenetic Alopecia in Men: Multifactor Analysis
Both genetics and lifestyle factors contribute to male pattern baldness.
research Metformin And Malignant Neoplasms: A Possible Mechanism Of Antitumor Action And Prospects For Use In Practice
Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.
research Androgens and Antiandrogens Influence on COVID-19 Disease in Men
Male hormones may make COVID-19 worse, while substances that block these hormones could lessen symptoms.
research Dermatological Aspects of Significance of Hyperandrogenism for Polycystic Ovary Syndrome
Hirsutism and acanthosis nigricans are important for diagnosing PCOS; dermatologists play a key role in early detection and treatment.
research Efficiency Research of the Comprehensive Hair Loss Treatment
The comprehensive treatment with biomimetic peptide lotion was effective for hair loss.
research The Development of Portal Hypertension and Liver Failure Due to Long-Term Intake of Vitamin A in a Young Woman: Case Report
A young woman got liver damage from taking too much vitamin A for two years.
research Alopecia and Clinical Presentation of Endocrinopathies: Pathogenetic and Diagnostic Aspects
Hormonal imbalances can cause hair loss, and understanding them can help develop better treatments.
research Features of Hyperandrogenism in Men
Androgen levels can increase at any age, affecting symptoms like acne, hair loss, and prostate size.
research Alopecia Areata as a Clinical Manifestation of Autoimmune Inflammation Due to Vitamin D Deficiency
Lack of vitamin D might cause hair loss due to autoimmune problems, and fixing vitamin D levels could help treat it.
research Modern Approaches to the Therapy of Androgenic Alopecia
research Trichology Features of Alopecia in Women of Reproductive Age Patients with Polycystic Ovary Syndrome
Women of reproductive age with polycystic ovary syndrome often experience hair loss.
research Molecular, Biological, and Clinical Aspects of the Use of Platelet-Rich Plasma in the Treatment of Androgenetic Alopecia
research Phototrichogram as a Tool to Assess the Effectiveness of Minoxidil Therapy in Patients with Androgenetic Alopecia
research Psycho-Emotional Conditions of Patients with Non-Scarring Alopecia (Circumscribed, Androgenetic)
Patients with non-scarring alopecia often experience emotional disorders like depression and stress.
research Spironolactone Therapeutic Effect in the Hyperandrogenism Syndrome
Spironolactone effectively reduces symptoms of hyperandrogenism like hirsutism and acne.
research Androgen Status in Patients with Androgenetic Alopecia
Men with male pattern baldness may not have different hormone levels, but their hair follicles are likely more sensitive to hormones.