Clinical Signs and Laboratory Tests for the Differential Diagnosis of Androgenic and Post-COVID-19 Alopecia in Women

    Irina N. Kondrakhina, Alexey A. Kondrakhin, Alexandr А. Nikonorov, Eugenia R. Gatiatulina, Dmitry G. Deryabin, А. А. Кубанов
    TLDR Post-COVID-19 hair loss is different from androgenetic alopecia and can be identified by lower copper and higher selenium levels.
    The study identifies objective criteria for differentiating between androgenetic alopecia (AGA) and post-COVID-19 alopecia in women. It found that post-COVID alopecia presents as diffuse telogen effluvium, unlike AGA, which affects hair follicles in specific phases. Both conditions showed elevated dihydrotestosterone levels, but post-COVID patients had significantly lower copper (46.4% lower; p=0.006) and higher selenium levels (24.7% higher; p=0.003) compared to AGA patients. These findings, analyzed using the CART algorithm, provide a basis for effective differentiation and targeted conservative therapy for these types of hair loss.
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