The Role of Exosomes in the Diagnosis and Treatment of Immune Mediated Dermatosis, Treatment of Skin Wounds and Alopecia

April 2024 in “ Vestnik dermatologii i venerologii ”

Revaz Zenaishvili, Nadezhda Palkina, Т. Г. Рукша

exosomes immune-mediated dermatosis skin wounds alopecia biomarkers immune responses wound healing hair growth exosome therapy

TLDR Exosomes show promise for diagnosing and treating skin conditions and hair loss.

The document discusses the role of exosomes, small vesicles released by cells, in diagnosing and treating immune-mediated dermatosis, skin wounds, and alopecia. Exosomes can be used as biomarkers for these conditions, providing a non-invasive diagnostic tool. They also have therapeutic potential due to their ability to modulate immune responses, promote wound healing, and stimulate hair growth. In a study involving 200 alopecia patients, those treated with exosome therapy showed significant hair regrowth compared to the control group. However, more research is needed to standardize the identification characteristics of exosomes and to develop technologies for their large-scale production.

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Research cited in this study

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

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The Role of Exosomes in the Diagnosis and Treatment of Immune Mediated Dermatosis, Treatment of Skin Wounds and Alopecia

Research cited in this study

research Biomaterials Functionalized with MSC Secreted Extracellular Vesicles and Soluble Factors for Tissue Regeneration

research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics

research Regulation of Hair Follicle Development by Exosomes Derived from Dermal Papilla Cells

research Exosomes as a Novel Pathway for Regulating Development and Diseases of the Skin

research Extracellular Vesicles Derived from MSCs Activate Dermal Papilla Cells In Vitro and Promote Hair Follicle Conversion from Telogen to Anagen in Mice

research Hair Regeneration Therapy: Application of Adipose-Derived Stem Cells

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