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Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Different types of androgens bind differently to two receptors, AR1 and AR2, in Atlantic croaker's brain and ovarian tissues, suggesting these receptors may control different androgen actions in fish.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.

Maintaining DNA integrity in stem cells is crucial to prevent aging and cancer.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

A new carrier improves skin delivery of tofacitinib for treating inflammatory skin diseases.

RU 58841 may treat acne, hair loss, and excessive hair growth.

RUM-loaded SLN shows promise for treating acne and hair loss topically.

Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.

Liposomes can make the antiandrogen RU 58841 more effective for skin application by reducing absorption, increasing skin retention, and targeting sebaceous structures.

Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.

The nature of the side chain in RU 58841 derivatives greatly affects its AR affinity, with the N-(iodopropenyl) derivative 13 showing the highest AR binding affinity, suggesting its potential for developing high-affinity radioiodinated AR radioligands.

Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

Glucocorticoids and sex hormones affect skin health, with potential for targeted treatments to minimize side effects and treat skin conditions.

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Researchers made stem cells from human hair follicle cells with higher efficiency than from skin cells.

The review says that stem cells are beneficial for making skin replacements.

Some epilepsy drugs can cause reproductive and cosmetic side effects in women and affect pregnancy, but most women still have healthy babies.

Both genetics and lifestyle factors contribute to male pattern baldness.

Metformin, a diabetes drug, may also help fight cancer, but more research is needed to understand how.

Male hormones may make COVID-19 worse, while substances that block these hormones could lessen symptoms.

Hirsutism and acanthosis nigricans are important for diagnosing PCOS; dermatologists play a key role in early detection and treatment.

The comprehensive treatment with biomimetic peptide lotion was effective for hair loss.