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Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Spironolactone treatment increases the amount of testosterone available in the body.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

A protein from certain immune cells is key for new hair growth after skin injury in mice.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Hair loss affects women's mental health more than men's, causing anxiety, low self-esteem, and social insecurity.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Laser hair removal is the most requested cosmetic procedure and has become a scientifically-based treatment suitable for all skin types.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Hair loss common in Australia; men affected earlier, more often than Asians; women less concerned.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.