Tacrolimus in Dermatologic Disorders
May 2001
in “
Annals of pharmacotherapy/The annals of pharmacotherapy
”
TLDR Topical tacrolimus is safe and effective for skin conditions, but oral tacrolimus has serious side effects.
The document reviewed the use of tacrolimus for various skin disorders, finding that topical tacrolimus was a safe and effective short-term treatment for conditions like atopic dermatitis and mucosal lichen planus. Oral tacrolimus was effective for recalcitrant plaque psoriasis but had severe adverse effects, including infections and nephrotoxicity. Further studies were recommended to assess long-term safety and optimal dosage.
