An Unusual Variant of Granulomatous Adnexotropic Cutaneous T-Cell Lymphoma

    February 2003 in “ British Journal of Dermatology ”
    A Garcovich, Simone Garcovich, Guido Massi
    TLDR A rare type of skin lymphoma was identified, affecting hair follicles and sweat glands.
    A 40-year-old man experienced a 6-year progression of pruritic erythematous lesions and alopecia on various body parts, including the scalp and beard. Initially diagnosed as chloracne due to cysts and comedones, further biopsy revealed a lymphocytic infiltrate affecting eccrine glands and hair follicles, consistent with syringotropic cutaneous T-cell lymphoma (CTCL) and pilotropic mycosis fungoides. The follicles were surrounded by dense lymphocytic infiltrates, with some transforming into structures resembling neoplasms like basal cell carcinoma. This case highlighted an unusual variant of granulomatous adnexotropic CTCL, characterized by follicular and eccrine gland involvement.
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