An Unusual Variant of Granulomatous Adnexotropic Cutaneous T-Cell Lymphoma
February 2003
in “
British Journal of Dermatology
”
Studysummary This case study describes a 40-year-old man diagnosed with pilotropic mycosis fungoides, a form of folliculotropic cutaneous T-cell lymphoma, characterized by lymphocytic infiltration of hair follicles and eccrine glands.
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A 40-year-old man experienced a 6-year progression of pruritic erythematous lesions and alopecia on various body parts, including the scalp and beard. Initially diagnosed as chloracne due to cysts and comedones, further biopsy revealed a lymphocytic infiltrate affecting eccrine glands and hair follicles, consistent with syringotropic cutaneous T-cell lymphoma (CTCL) and pilotropic mycosis fungoides. The follicles were surrounded by dense lymphocytic infiltrates, with some transforming into structures resembling neoplasms like basal cell carcinoma. This case highlighted an unusual variant of granulomatous adnexotropic CTCL, characterized by follicular and eccrine gland involvement.