Efficacy of Oral Apremilast in the Treatment of Alopecia Areata at the Tertiary Care Hospital, Karachi

    December 2023 in “ Journal of health and rehabilitation research ”
    Parisa Sanawar, Rabia Ghafoor, Khusru Asadullah, Nusrat Jabeen, Farhan Ahmed Siddiqui, Misbah Qadir
    Image of study
    TLDR Oral Apremilast effectively treats alopecia areata in most patients.
    The study conducted at Jinnah Postgraduate Medical Centre in Karachi assessed the efficacy of oral Apremilast in treating alopecia areata (AA) in 85 patients. Administered at 30 mg twice daily, Apremilast significantly reduced the Severity of Alopecia Tool (SALT) scores from 62.42 to 41.53 over 12 weeks, with a mean difference of 20.89 (p-value: 0.0001). The treatment was effective in 80% of patients, suggesting that oral Apremilast could be a promising alternative for AA treatment, warranting further clinical investigation.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  43 upvotes 1 year ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  407 upvotes 9 months ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 3 weeks ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Oral fin/min/biotin Stack 2 month progress pics

      in Progress Pictures  14 upvotes 6 days ago
      The conversation is about a user's progress with an oral treatment for hair loss using a stack of finasteride, minoxidil, and biotin over two months, noting stabilization after an initial shed. The user mentions using Hims Chews, which are effective but costly, and another user comments that biotin is ineffective.

      community Do you think oral minoxidil will become the standard for hair loss in 2026?

      in Minoxidil  143 upvotes 1 week ago
      Oral minoxidil is considered more convenient and effective for some users, with positive results reported, but concerns about side effects and availability persist. Finasteride remains a standard treatment, while some users explore combinations with other treatments like dutasteride and laser devices.

    Related Research

    1 / 1 results