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In this study, classic PDRN (50-1,500 kDa) was observed to improve wound healing quality in a mouse model by enhancing collagen composition and cell migration.

This study found that selective inactivation of ribonucleotide excision repair in mouse epidermis led to spontaneous DNA damage, skin inflammation, and the development of squamous cell carcinoma, suggesting potential implications for cancer development in humans.

In this study, researchers identified key miRNAs and target genes involved in hair follicle development in Merino sheep, providing insights that could aid in improving sheep breeding for wool quality.

In this study, FGF5-knockout Dorper sheep generated using CRISPR/Cas9 showed increased fine-wool and active hair-follicle density, suggesting potential therapeutic applications for androgen alopecia.

This study found that ROR2 plays a crucial role in the regulation of hair follicle stem cell self-renewal and maintenance, particularly by compensating for the absence of β-catenin.

This study identified key mRNAs and lncRNAs, along with related pathways, that play potentially important roles in hair follicle development and cycling in cashmere goats.

This study found that Frizzled genes Fzd3 and Fzd6 are redundantly involved in controlling hair follicle polarity in mice, but operate through distinct mechanisms, highlighting their complex role in hair orientation.

This study revealed specific patterns and potential functions of long non-coding RNAs during the hair follicle cycle of yaks, offering insights into their sequence conservation between yaks and cashmere goats.

This study found that the protein Formin 2 helps regulate cell-to-cell transport in thale cress by stabilizing actin filaments at plasmodesmata, with its absence leading to increased permeability and vulnerability to viral infections.

This study concluded that macrophage iron retention due to Ferroportin inactivation hinders skin wound healing but does not affect liver damage or fibrogenesis in a mouse model.

This study identified specific microRNAs and genes associated with the differing wave patterns in Hu sheep hair follicles, which may help understand the molecular mechanisms behind wool quality.

This review discusses hydrogel-forming microneedles for non-invasive drug delivery in dermatology and reports no new clinical results, emphasizing their promise in improving treatment adherence and patient comfort.

This study found that lncRNA-599554 contributes to the inductive ability of dermal papilla cells in cashmere goats by sponging miR-15a-5p, promoting Wnt3a expression, and potentially influencing hair follicle regeneration.

This study analyzed the genetics of the patchiness phenotype in New Zealand rabbits and found that the gene KRT82, with identified SNPs in its promoter, may serve as a potential biomarker for breeding these rabbits.

This study suggests that ROXYs and reactive oxygen species are likely involved in the signaling pathways plants use to respond to nitrate deprivation.

This study reports that familial frontal fibrosing alopecia was diagnosed earlier in premenopausal women compared to postmenopausal women, though long-term outcomes remain uncertain without a definitive treatment.

In this study, researchers found that miR-143-3p may play a novel role in cashmere growth by directly repressing the expression of Itga6 in secondary hair follicles of goats.

This study used a newly developed RP-HPLC method to accurately measure finasteride distribution in human cadaver skin after applying different vesicular drug delivery systems.

This study found that Egyptian women with frontal fibrosing alopecia had lower serum PPARγ levels and a higher occurrence of PPARG gene polymorphism compared to healthy controls, suggesting a potential role for PPARγ in the condition's development.

This review analyzes PDRN's molecular mechanisms and therapeutic applications in anti-aging dermatology but reports no new clinical results, highlighting the need for more standardized protocols and long-term evaluations.

This review discusses fibrosing frontal alopecia, including its causes, mechanisms, and treatments, and emphasizes the need for further research to improve understanding and treatments; it reports no new clinical results.

This study identified distinct and diverse fibroblast populations in female scalp cells that lose their signature and identity with age, highlighting significant age-related changes, such as increased fibrosis, DNA damage, and senescence, which may affect scalp dermal support for healthy hair follicles.

In this case study, a girl with hereditary vitamin D resistant rickets had a novel mutation in the VDR gene that affected hair cycling without causing total alopecia, suggesting ligand-independent VDR function in hair cycling.

This study describes the development of a monoclonal antibody, 005-C04, which blocks PRLR-mediated signaling, suggesting its potential for furthering understanding of PRLR's role in health and disease.

This study observed that innervation of the mystacial pad in rats by fine-caliber axons is more extensive and complex than previously described, with distinct differences in labeling patterns depending on the tracer and survival time.

This expert opinion article presents insights from dermatologists and aesthetic physicians on using polynucleotides (Rejuran®) for skin hydration, rejuvenation, structural support, barrier repair, and scar remodeling, noting their favorable safety profile but highlighting the need for more robust evidence and research.

This study found that mouse type II spiral ganglion neurites in vitro avoided laminin and high concentrations of fibronectin, indicating both can guide neurite paths differently than type I neurites.

In this study, a 75% ethanol extract of Fructus Psoraleae was found to significantly inhibit 5-α reductase and promote hair growth in mice, indicating its potential as a treatment for androgenetic alopecia through modulation of the Nrf2-Keap1 pathway.

This study found that nestin-expressing hair follicle-derived cells express higher levels of certain neurotrophic factors and neural markers, indicating potential for neuroregenerative therapy applications.