32 citations
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January 2007 in “Biological & Pharmaceutical Bulletin” This study found that combining minoxidil and retinol additively promoted hair growth in vitro, enhancing Erk- and Akt-dependent pathways and preventing apoptosis in dermal papilla cells and keratinocytes.
16 citations
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September 2019 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that the retinol dehydrogenases SDR16C5 and SDR16C6 in mice play a crucial role in skin retinol dehydrogenase activity, affecting hair growth and gland functions without impacting survival.
16 citations
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August 1989 in “PubMed” This study concluded that high-dose oral therapy with L-cystine, gelatin, and vitamin A significantly improved hair growth indicators in patients with diffuse hair loss, with no systemic side effects observed.
2 citations
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July 1982 in “British Journal of Dermatology” This study reports that retinol acetate inhibited the pro-oxidant effects of benoxaprofen on polymorphonuclear leucocytes in vitro.
1 citations
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December 2022 in “Journal of applied biological chemistry” This study found that TRP-hair essence significantly protected and improved the quality of human hair, particularly against heat stress, by enhancing cuticle health and maintaining hair color.
This study found that the RN-Lip co-delivery system enhanced the stability and skin permeation of retinol and niacinamide, leading to improved anti-aging and skin-brightening effects in vitro.
January 2025 in “ARC Journal of Clinical Case Reports” This case report suggests that using encapsulated retinol in polylysine may effectively treat actinic keratosis with minimal irritation, potentially providing a safer alternative for frequent use.
September 2016 in “Journal of the Egyptian Women's Dermatologic Society (Print)” This article explores the interactions between retinoids and the immune system but reports no new clinical results related to their role in hair cycle control.
6 citations
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June 2011 in “British Journal of Dermatology” This study found that individuals with alopecia areata had significantly higher serum levels of retinol-binding protein 4 and increased IgG immunoreactivity against it, suggesting a role in the disease's pathogenesis.
January 2026 in “Dermatologic Therapy” This study found that elevated tissue RBP4 levels correlate with disease severity in alopecia areata and decrease after effective baricitinib treatment, while the rs3758539 polymorphism is linked to disease susceptibility but not to treatment response.
44 citations
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April 2008 in “The Journal of Clinical Endocrinology & Metabolism” This study concluded that although RBP4 and adiponectin levels are associated with visceral fat, they do not independently contribute to the development of PCOS.
14 citations
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March 2019 in “European journal of pharmaceutics and biopharmaceutics” This study observed that proretinal nanoparticles delivered significantly higher concentrations of retinal to the stratum corneum and hair follicles compared to non-particulate forms, potentially improving topical retinoid therapy.
January 2022 in “Menoufia Medical Journal /Menoufia Medical Journal” This study found that alopecia areata was associated with increased serum levels of retinol-binding protein-4 compared to controls, but no correlation with disease severity was observed.
8 citations
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November 2007 in “Skin Pharmacology and Physiology” In this study, skin stretching significantly increased the delivery of retinyl ascorbate into the dermis, while sealing hair follicles did not affect absorption through native skin.
1 citations
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October 2021 in “Journal of Medical Case Reports” This case report describes a possible association between topical 5% minoxidil use and inferior hemiretinal artery occlusion in a 21-year-old Asian Indian male with androgenic alopecia.
July 2026 in “Journal of the American Academy of Dermatology” This study found that patients with alopecia areata have a significantly higher risk of retinal abnormalities, suggesting common immune mechanisms, though the low absolute risk indicates that screening should be led by symptoms rather than done routinely.
October 2023 in “Indian journal of ophthalmology. Case reports” This case report described acute vision loss in a patient after forehead injections of triamcinolone acetonide for alopecia areata, attributing retinal artery occlusion to embolization by steroid particles.
258 citations
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July 2005 in “Journal of lipid research” This study found that DGAT1 exhibits additional acyltransferase activities in vitro, including MGAT, wax synthase, and ARAT activities, suggesting these could be relevant to its in vivo functions.
2 citations
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December 2018 in “Journal of cosmetic dermatology” This study observed a significant increase in cellular retinol-binding protein-1 expression in lesional skin of patients with alopecia areata compared to healthy controls, suggesting its potential role in the disease's pathogenesis.
In this case study, the researchers observed that a dermocosmetic formulation with encapsulated retinol led to complete regression of a chronic actinic keratosis lesion on the scalp, suggesting it may be a promising treatment approach.
April 2024 in “Rheumatology” This case report describes a 22-year-old woman whose initial manifestation of systemic lupus erythematosus was vision-threatening vaso-occlusive retinopathy, highlighting the need for early identification and multidisciplinary treatment.
In this study, a case was reported where oral Minoxidil led to severe ocular complications, specifically Central Retinal Vein Occlusion and Cilioretinal Artery Occlusion, resulting in sudden vision loss which improved upon discontinuation.
10 citations
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July 2023 in “World Journal of Stem Cells” This review discusses the interaction between mesenchymal stem cell secretomes and retinal cell secretomes, suggesting their potential in experimental therapies to protect and regenerate retinal tissue.
June 2023 in “Medeniyet medical journal” This study found that while the macular, retinal nerve fiber layer, and retinal layers' thickness were similar between alopecia areata patients and controls, the choroidal thickness was significantly thicker in the alopecia areata group, suggesting potential inflammation-related changes.
This case report describes retinal occlusion and medial canthal swelling in a 64-year-old female following the injection of acellular porcine urinary bladder matrix for hair restoration, a previously unreported side effect.
May 2024 in “Clinical and experimental optometry” This case report describes a rare side effect of finasteride in a young male being treated for androgenic alopecia.
3 citations
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March 2022 in “Medicine” This case report described a patient with unilateral branch retinal artery occlusion due to previously undiagnosed systemic lupus erythematosus, where systemic immunotherapy led to significant visual improvement and resolution of macular edema.
July 2024 in “Journal of Investigative Dermatology”
This study found that the Lim-homeodomain transcription factor Lhx2 regulates Sonic Hedgehog signaling during early retinal neurogenesis in mice by controlling the expression of pathway genes in retinal progenitor cells.
November 2007 in “Hospital pharmacy” This article discusses the importance of increasing awareness about specific adverse drug reactions, prevention methods, and the promotion of reporting ADRs to the FDA's MEDWATCH program; it reports no new results.