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This study demonstrated that a new topical treatment using ketotifen-loaded microneedles, designed for prolonged release, significantly reduced inflammatory markers in an animal model of allergic conjunctivitis, suggesting enhanced therapeutic delivery and sustained ocular benefits.

This study found that young men with early-onset androgenetic alopecia have a worse glycolipid profile and hormone pattern similar to women's PCOS, suggesting a possible male PCOS-equivalent syndrome.

In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.

In this study, researchers observed that Malassezia species show different lipid metabolism and growth patterns depending on pH, with slightly acidic conditions promoting beneficial lipid bio-conversion for skin health, while neutral pH resulted in lower growth and lipid content, potentially negatively impacting the skin.

This study found that when metabolism changes and extracellular glucose decreases, hippocampal CA3 neurons release ATP, which is converted to adenosine and reduces neuron excitability, enhancing the seizure threshold.

This review suggests that mesenchymal stem cells' therapeutic effects might be due to bioactive substances they release, rather than the cells themselves, highlighting the potential of the MSC secretome as a novel, cell-free therapeutic approach.

In this study, oral dutasteride treatment for at least 12 months was associated with either stabilization or improvement of male-pattern hair loss in the majority of patients.

This study investigated spanlastic nanovascular drug delivery systems and found that they can effectively enhance the transport and continuous release of medicines with small particle size, low polydispersity index, and satisfactory entrapment efficiency, showing potential as carriers for drug delivery.

This narrative review highlights the critical role of intracrine hormone production in peripheral tissues, suggesting that continuous-release subcutaneous testosterone pellet therapy may offer a more effective symptom-driven approach for aging populations, though large-scale randomized controlled trials are needed for confirmation.

In this study, exposure to e-cigarette vapor was reported to trigger the release of proinflammatory cytokines IL-6, IL-8, and IL-10, which could contribute to dermatological issues.

This study on Dorper sheep identified important genetic factors influencing hair follicle development, finding that expression patterns and genes like DBI, FZD3, and ZDHHC21 play a crucial role in wool shedding, which could help improve understanding of mammalian skin-related traits and human hair advancement.

This study developed and characterized Quercetin-loaded nanogels, finding that they showed promising potential for enhanced drug delivery and stability in treating Alopecia, with an optimized batch achieving a drug release of 95.32% over 12 hours.

This study suggests that hormonal changes may contribute to the persistent symptoms of long COVID, with specific patterns observed in serum hormone levels related to fatigue and sensory dysfunction.

This study identified intramembrane proteolysis as a key feature of Astrotactin2 maturation, providing insights into its role in planar cell polarity hair patterning.

This study found that nano-transferosomal gel formulations of finasteride improved its delivery across skin layers, potentially reducing major side effects associated with oral administration for treating male pattern baldness.

This study found that nano-sized minoxidil formulations significantly increased skin penetration and follicular drug delivery for alopecia areata treatment, compared to conventional ethanol-based solutions, and demonstrated effective controlled release over six hours.

This study reviews the potential of electrospun nanofiber mats as innovative drug delivery systems for wound healing, emphasizing their ability to enhance drug release, improve cell adhesion, and promote tissue regeneration by incorporating antibiotics, growth hormones, or stem cells.

This research highlights the potential of emulgel as an advanced topical drug delivery system, offering improved efficacy for hydrophobic medications in treating dermatological conditions and a range of ailments with its dual release control mechanism of gel and emulsion.

In this study, researchers developed an in-situ gel formulation of antibacterial Levofloxacin for the eye, which showed prolonged drug release, increased residence time, and effective antibacterial action, suggesting it may be a safe and effective ocular delivery system for antibiotics.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.

This review discusses the shedding phase of the hair cycle, known as exogen, and reports no new findings while analyzing related processes like club fiber formation and release.

This study identified changes in transcription factor gene expression across various signaling pathways during inner ear hair cell regeneration in birds, revealing patterns and potential new pathways for future investigation.

This study reported new crystallographic structures and polymorphs of finasteride, including several solvates with distinct X-ray diffraction patterns and thermally characterized properties.

This study suggests that finasteride-loaded liquid crystalline nanoparticles could be a viable alternative to oral administration for treating androgenetic alopecia due to their controlled release and skin permeation properties.

This review discusses chemotherapy-induced alopecia, highlighting its pathogenesis, clinical patterns, and current therapeutic approaches, with no new clinical results reported.

This study compared the microscopic treatment zones created by different fractional lasers and radiofrequency in swine skin, finding distinct patterns and damage levels for each technology.

This study found that in wound-induced hair neogenesis, African spiny mice and laboratory mice exhibit different morphogenetic field formation patterns related to tissue stiffness, suggesting evolutionary developmental biology advantages.

This study found that acne inversa is primarily an epithelial-driven disease, with cyst-forming tendrils causing inflammation due to rupture and the release of debris, highlighting limitations of punch biopsies for analysis.

In this study, researchers identified specific long non-coding RNAs involved in feather development that do not follow traditional genetic inheritance patterns in chickens.