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Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

Some drugs can cause skin, nail, and hair problems, which are important for healthcare professionals to recognize and report.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Activating TRPV3 stops human hair growth.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

New treatments for Alopecia Areata show promise but need to be more effective and affordable.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.

Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.

Oxidative stress affects hair loss in men with androgenetic alopecia.