56 citations
,
July 2005 in “Journal of The American Academy of Dermatology” This study found that vertical sections of alopecia biopsy specimens had a higher concordance rate with the original combined diagnosis compared to transverse sections alone, although both methods have their pros and cons.
53 citations
,
October 2014 in “Free radical biology & medicine” This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.
44 citations
,
January 2006 in “Biological & Pharmaceutical Bulletin” This research suggests that testosterone-induced expression of TGF-beta1 and type I procollagen may lead to perifollicular fibrosis in androgenetic alopecia, with finasteride inhibiting this process as a possible mechanism for its effects.
30 citations
,
July 2022 in “Scientific Reports” This study developed a model using cardiovascular radiomics to estimate biological heart age, finding obesity and other health factors strongly correlated with accelerated heart aging.
21 citations
,
July 2019 in “Cardiovascular Research” This study found that prenatal exposure to androgens caused long-lasting heart remodeling and left ventricular hypertrophy in female mice offspring, suggesting potential cardiac risks for daughters of mothers with PCOS.
21 citations
,
January 2006 in “Pediatrics” This review discusses how certain genetic, infectious, and metabolic conditions might influence disease severity and highlights the potential for new therapies, but it presents no new research findings.
19 citations
,
February 2018 in “Lasers in Medical Science” This study found that 655-nm red light with LED enhanced hair shaft elongation and reduced catagen transition in human hair follicles in vitro by activating the Wnt/ß-catenin signaling pathway.
17 citations
,
September 2012 in “Dermatologic Clinics” This review discusses histologic findings in alopecia and emphasizes the importance of understanding normal follicular anatomy and cycles in transverse sections, without reporting new results.
15 citations
,
January 2022 in “Journal of Oleo Science” This study found that a phytosomal delivery system improved the bioavailability of Cuscuta reflexa extract compared to the plain extract, suggesting enhanced potential for this formulation.
14 citations
,
October 2020 in “Scientific reports” This study found that ATM protein plays a crucial role in protecting human hair follicle melanocytes from oxidative stress, which is linked to the greying of hair.
12 citations
,
January 2014 in “Annals of Dermatology” This study found an association between hydroxyl radical-modified SOD and alopecia areata, suggesting these modifications may lead to antibody induction in the condition.
9 citations
,
August 2017 in “Photochemistry and Photobiology” This study found that isolated red light may serve as an alternative for photo-immunotherapy without additional photosensitizers, as it did not reduce keratinocyte differentiation markers or increase photo-oxidative damage, unlike treatment with IL-4 or UVA1/blue light.
8 citations
,
February 2015 in “Cellular immunology” This study found that deleting Snai2 and Snai3 genes in mice disrupts immune cell development, resulting in severe autoimmunity and early death due to the loss of immune tolerance.
6 citations
,
September 2019 in “Skin pharmacology and physiology” This study found that RCS-01 cell therapy for aged skin was well tolerated and associated with increased gene expression related to extracellular matrix homeostasis, suggesting potential skin improvement.
6 citations
,
January 2019 in “International Journal of Medicine in Developing Countries” This study found that premature greying of hair was reported in 42.5% of young adults from King Faisal University, with higher prevalence among females, and noted associations with various health and lifestyle factors.
6 citations
,
July 2018 in “Scientific Reports” In this study, gene expression changes in rat whisker follicles after methamphetamine administration may serve as indicators of the drug's rewarding effects and potential addiction pathways.
5 citations
,
June 2022 in “Frontiers in immunology” This study observed that expanding regulatory T cells in the skin of mice with alopecia areata did not reverse the condition, indicating that additional immunotherapy may be necessary.
4 citations
,
January 2025 in “Journal of Materials Chemistry B” In this study, researchers developed a multifunctional, injectable hydrogel that adapts to irregularly shaped wounds, enhances healing, and shows potential antibacterial activity without significant toxicity, suggesting promise for treating chronic wounds.
4 citations
,
June 2013 in “The Journal of Rheumatology” This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.
4 citations
,
July 1994 in “Clinics in Dermatology” This review discusses the emergence and impact of eosinophilia-myalgia syndrome related to L-tryptophan and offers insights into environmental factors affecting sclerodermatous conditions, with no new research findings presented.
3 citations
,
January 2023 in “Agriculture and Natural Resources” This study found that flower extracts of Wedelia trilobata may serve as a promising active ingredient for cosmeceutical products due to their antioxidant, anti-inflammatory, and antimicrobial properties.
3 citations
,
May 2018 in “Experimental Dermatology” In this study, the researchers reported that patient impacts and symptoms of hidradenitis suppurativa, as assessed by HSIA and HSSA measures, are associated with clinical characteristics such as the number of abscesses and inflammatory nodules.
1 citations
,
October 2025 in “Nano Research” In this study, researchers developed a dissolvable microneedle patch combining HA-TEMPO and Portulaca oleracea L.-derived nanoparticles, which effectively reduced oxidative stress and inflammation in an atopic dermatitis model while restoring immune balance, suggesting a promising treatment strategy.
1 citations
,
May 2025 in “Scientific Reports” In this study, researchers found no significant differences in serum levels of DHEAs, DHT, and testosterone between female patients with oral lichen planus and healthy controls, suggesting no neuroendocrine etiology linked to the condition.
1 citations
,
January 2024 in “Curēus” This case study reported significant clinical improvement in a 26-year-old male with dissecting cellulitis of the scalp after treatment with upadacitinib, suggesting that JAK inhibitors may be a promising option for refractory cases, where standard treatments have limited success.
1 citations
,
September 2023 This study reported that the combination of tridax procumbens and ginger juice improved antioxidant activity and protected against liver damage induced by paracetamol in rats, suggesting a potent hepatoprotective effect.
1 citations
,
July 2022 in “Functional foods in health and disease/Journal of functional foods in health & disease” This study found that oral probiotic supplementation over 12 weeks may improve hair growth, skin condition, metabolic health, and stress responses in Chinese adults with hair loss and a high risk of metabolic syndrome.
1 citations
,
January 2019 in “Advances in Medical Sciences” This study found that a combination of azelaic acid, minoxidil, and caffeine significantly reduced skin flap necrosis in rats, likely by increasing nitric oxide content and iNOS expression, compared to individual treatments.
1 citations
,
January 2015 in “Der pharmacia lettre” This study found that neurosteroids might play a role in the neuroprotective effects of ischemic postconditioning by reducing brain infarct size and improving motor performance and memory in mice.
July 2026 in “Gazi Medical Journal” This study reported that obese women with polycystic ovary syndrome had higher body fat and insulin resistance, and lower HDL cholesterol compared to non-obese patients and healthy controls.