The Serum Evaluation of Sex Hormones Including DHEAs, DHT, Testosterone in Oral Lichen Planus Patients
May 2025
in “
Scientific Reports
”
TLDR Sex hormones do not cause oral lichen planus.
This study examined serum levels of sex hormones (DHT, DHEAs, and testosterone) in 40 female oral lichen planus (OLP) patients compared to 40 healthy controls. Results showed no significant differences in hormone levels between OLP patients and controls, nor between menopausal and non-menopausal participants, or between different OLP types. The study concludes that sex hormones do not contribute to OLP pathogenesis, indicating no neuroendocrine etiology related to these hormones. The study's limitations include its small sample size and focus on females, suggesting the need for further research with a larger, more diverse group.