TLDR Sex hormones do not cause oral lichen planus.
This study examined serum levels of sex hormones (DHT, DHEAs, and testosterone) in 40 female oral lichen planus (OLP) patients compared to 40 healthy controls. Results showed no significant differences in hormone levels between OLP patients and controls, nor between menopausal and non-menopausal participants, or between different OLP types. The study concludes that sex hormones do not contribute to OLP pathogenesis, indicating no neuroendocrine etiology related to these hormones. The study's limitations include its small sample size and focus on females, suggesting the need for further research with a larger, more diverse group.
4 citations
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June 2017 in “Endocrine Reviews” Dihydrotestosterone (DHT) mainly affects nearby cells, doesn't significantly change prostate hormonal environment or cancer risk, and doesn't play a main role in causing hair loss or acne. More research is needed on its effects on heart health, sexual function, and bone health.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
14 citations
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January 2018 in “Advances in Clinical Chemistry” The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
Hormonal treatments can help with hair loss, acne, and excess hair growth, but it takes 3-6 months to see results and patients should know the possible side effects.
58 citations
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November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
6 citations
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September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
