TLDR Upadacitinib significantly improved a man's severe scalp condition when other treatments failed.
A 26-year-old male with recalcitrant dissecting cellulitis of the scalp (DCS) showed significant clinical improvement after a short course of upadacitinib, a Janus kinase (JAK) inhibitor. Previous treatments, including topical antimicrobials, oral antibiotics, corticosteroids, and intralesional triamcinolone injections, had limited success. Upadacitinib reduced the patient's pain, pustular draining, and bleeding, and improved his quality of life. This case suggests that JAK inhibitors may be a promising therapy for refractory DCS, a condition with few effective treatment options.
2 citations,
March 2023 in “Frontiers in medicine” A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.
48 citations,
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2 citations,
March 2023 in “Frontiers in medicine” A 15-year-old boy's severe scalp condition improved significantly with adalimumab and baricitinib treatment.
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51 citations,
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36 citations,
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33 citations,
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