January 2022 in “International Journal of Trichology” This study found that combining minoxidil with PRP therapy significantly improves hair density, shaft diameter, and reduces vellus and telogen hair proportions in men with androgenetic alopecia compared to either treatment alone.
142 citations
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February 1985 in “Fertility and sterility” This study found that spironolactone reduced serum androstenedione and anagen hair shaft diameter in hirsute patients but did not significantly alter unbound testosterone levels, suggesting its effects are primarily peripheral.
53 citations
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January 1985 in “Acta obstetricia et gynecologica Scandinavica” This study found that an 8-month treatment with a low-dose oral contraceptive significantly reduced testosterone levels and hair growth in women with polycystic ovary syndrome and hirsutism, with minimal side effects.
2 citations
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December 1994 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study concluded that a regimen of transdermal estradiol and oral medroxyprogesterone acetate effectively reduces hirsutism while minimizing side effects in women with polycystic ovary syndrome.
November 2022 in “Molecular Pharmaceutics” This study found that intradermal injection of a cell-penetrating, AR-targeting asiRNA promoted hair growth and reduced androgen receptor expression in mouse models of androgenetic alopecia, suggesting its therapeutic potential.
14 citations
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April 2020 in “Journal of Cosmetic Dermatology” In this study, intradermal injections of QR678 were found to significantly reduce hair fall in men with androgenetic alopecia over 6 months, with superior improvements in hair density and thickness compared to PRP.
December 2025 in “The American Journal of Interdisciplinary Innovations and Research” This study operationalizes a four-step workflow for selecting donor hair for capsule extensions, translating surgical trichology insights into an extension-specific protocol to enhance natural hair optics and biomechanics, suitable for premium extension services.
April 2022 in “Journal of Cosmetic Dermatology” In this study, combining platelet-rich plasma and platelet gel treatments significantly reduced hair loss and increased hair density and diameter in patients with resistant androgenic alopecia, leading to high patient satisfaction.
46 citations
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August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” In this study, ketoconazole treatment improved acne in all women and reduced hirsutism in some, but it caused several side effects and requires careful monitoring.
July 2009 in “Medical & surgical dermatology” Low-dose acitretin helps nail psoriasis, stem cells may treat scarring alopecia, Chinese men have lower baldness rates, lateral foldplasty is good for ingrown toenails, hair diameter helps diagnose female baldness, childhood trauma linked to alopecia areata, certain hair-weaving leads to scalp conditions in African American women, and new methods for hair research and understanding hair and sweat gland development were introduced.
July 2025 in “Journal of Oncology Research and Therapy” This study found that the effectiveness of scalp cooling in preventing chemotherapy-induced alopecia in early-stage breast cancer patients depends on the integrity of the follicular pigmentary unit, particularly consistent melanosome quantity.
84 citations
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February 1981 in “Journal of Endocrinology” This study found that epidermal growth factor decreased hair growth rate and altered hair characteristics in neonatal mice, with some effects persisting into subsequent hair generations.
69 citations
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January 2015 in “Current problems in dermatology” This review discusses trichoscopy as a noninvasive, effective technique for diagnosing various hair loss conditions and monitoring treatment, highlighting its potential to reduce scalp biopsy necessity.
18 citations
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March 2010 in “Gynecologic and obstetric investigation” This study found that both combined therapy with goserelin and oral contraceptives, and oral contraceptives alone, significantly reduced hair diameter in severe hirsutism without a significant difference between treatments.
September 2025 in “Cosmetics” In this study, oral supplementation with NMN for 12 weeks in middle-aged Japanese women significantly increased hair growth density and diameter and improved subjective assessments of hair texture and quality of life, with no significant changes in hair hormone concentrations observed.
December 2024 in “Research Square (Research Square)” In this phase I/II clinical trial, placenta-derived mesenchymal stem cell exosome therapy significantly improved hair density and diameter, and reduced hair loss in patients with androgenetic alopecia, though further large-scale studies are needed to confirm these results and investigate the underlying molecular mechanisms.
27 citations
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February 2017 in “Biomedicine & Pharmacotherapy” This study found that white wax and its extract may promote hair growth in a mouse model of androgenetic alopecia by inhibiting 5α-reductase activity and increasing cell proliferation, with efficacy surpassing finasteride.
2 citations
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March 2023 in “Biomedicine & pharmacotherapy” This study found that platelet lysate significantly improved hair growth and follicle performance in both experimental settings and AGA patients, showing results comparable to platelet-rich plasma.
September 2025 in “Pharmaceutics” In this study, quercetin nanocrystals stabilized with glycyrrhizic acid were developed as a new treatment strategy for androgenetic alopecia, which significantly reduced DHT levels and improved hair regrowth in a mouse model, indicating synergistic potential for clinical application.
September 2024 in “Journal of Clinical and Nursing Research” This study found that combining Chuzhi Shengfa Tablets with either ketoconazole shampoo or 5% minoxidil foam significantly improved hair density, hair diameter, and reduced scalp oil in men with androgenetic alopecia, without increasing adverse reactions.
November 2023 in “Translational Medicine Communications” In this study, researchers found that Derinat, a TRPCs inhibitor, reduced oxidative stress and prolonged the anagen phase of hair growth in mice, supporting its potential as a therapy for androgenetic alopecia by improving clinical outcomes and enhancing quality of life for those affected.
1 citations
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January 1996 This study found that cysteine and arginine are crucial for hair growth in hair follicles, with cysteine affecting hair fibre diameter and arginine involved in protein incorporation and energy metabolism.
September 2016 in “Journal of dermatological science” This study identified TSC2 as an important regulator of hair follicle morphogenesis and patterning, with Tsc2cKO mice showing altered hair patterns and frequencies compared to controls.
46 citations
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April 1971 in “American Journal of Clinical Nutrition” Lack of protein causes hair root damage, but it can be reversed by eating protein again.
32 citations
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December 1969 in “The Lancet” This study found a significant shift to the telogen phase in the hair growth of children with classical marasmus compared to normal children, suggesting a connection to the chronicity of the condition.
4 citations
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February 2025 in “Nutrients” This randomized controlled trial found that consuming *Gynostemma pentaphyllum* extract significantly improved hair elasticity, density, and diameter over 24 weeks without severe adverse events, suggesting it as a safe functional food ingredient for hair health improvement.
In this 24-week study, oral supplementation with hydrolyzed low-molecular-weight porcine placental peptides significantly improved scalp elasticity, hair diameter, tensile strength, surface roughness, and luster compared to placebo, suggesting its potential as a nutritional intervention for age-related scalp and hair changes.
11 citations
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September 2012 in “Journal of animal physiology and animal nutrition” This study demonstrated that mink hair growth and pelt quality significantly depend on dietary protein levels and DL-methionine supplementation during the growing-furring period.
1 citations
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March 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, a new leave-on hair treatment with Dynagen and zinc salts significantly increased hair growth rate, fibre diameter, and follicle strength in healthy women.
April 2026 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study, supplementing adult Bichon Frises with 600 mg/kg Omega-3 PUFAs significantly improved their skin health, hair quality, feeding behavior, and metabolic health, compared to a control diet, over six weeks.