July 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
71 citations,
November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Edar signaling is crucial for proper hair follicle development and function.
43 citations,
December 2006 in “The American journal of pathology” Edar signaling is crucial for controlling hair growth and regression.
12 citations,
October 2021 in “Cells” Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.
236 citations,
July 2001 in “Trends in Molecular Medicine” Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.
70 citations,
February 2015 in “Expert Opinion on Drug Discovery” Topical drugs and near-infrared light therapy show potential for treating alopecia.
1 citations,
December 2023 in “Biomolecules” Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.
4 citations,
June 2023 in “Journal of developmental biology” The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.
60 citations,
March 2011 in “Proceedings of the National Academy of Sciences of the United States of America” RANK-RANKL signaling is essential for hair growth and skin health.
35 citations,
April 2008 in “Human Molecular Genetics” Skin and hair can help us understand organ regeneration, especially how certain stem cells might be used to form new organs.
2 citations,
January 2014 in “Hair therapy & transplantation” New treatments for hair growth disorders are needed due to limited current options and complex hair follicle biology.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
115 citations,
December 2017 in “Wiley Interdisciplinary Reviews-Developmental Biology” Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
170 citations,
November 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
10 citations,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
7 citations,
December 2021 in “Pharmaceutics” Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.
149 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
117 citations,
November 2006 in “Experimental Dermatology” The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.
24 citations,
October 2014 in “Cold Spring Harbor Perspectives in Medicine” Genetic research has advanced our understanding of skin diseases, but complex conditions require an integrative approach for deeper insight.
1 citations,
December 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Keeping β-catenin levels high in mammary cells disrupts their development and branching.
22 citations,
March 2021 in “Materials Today Bio” Scaffold-based strategies show promise for regenerating hair follicles and teeth but need more research for clinical use.
265 citations,
July 2012 in “Cell” The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.
32 citations,
April 2016 in “Journal of Investigative Dermatology” STAT5 activation is crucial for starting the hair growth phase.
383 citations,
February 2011 in “Nature Reviews Genetics” DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.
86 citations,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
82 citations,
February 2017 in “Cold Spring Harbor Perspectives in Biology” The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.
42 citations,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Sweat gland development involves two unique skin cell programs and a temporary skin environment.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
9 citations,
January 2017 in “Elsevier eBooks” Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.