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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Frizzled receptors are essential for various body development processes and maintaining certain body functions.

Activating TRPV3 stops human hair growth.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Prolactin affects hair growth cycles and can cause early hair follicle regression.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Minoxidil boosts hair growth by targeting adenosine and possibly sulfonylurea receptor 2B.

A certain smell receptor in hair follicles can affect hair growth when activated by a synthetic sandalwood scent.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

Skin has specialized touch receptors that can tell different sensations apart.

High-dose androgen therapy can help manage certain types of androgen resistance.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

E211 G>A gene linked to lower risk of severe prostate cancer and hair loss.

Prolactin affects when mice shed and grow hair.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

Genetic differences may affect COVID-19 deaths; anti-androgens could be potential treatment.

Estradiol stops hair growth in mice, but an antagonist can reverse this effect.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

A new protein was made to detect specific skin cell growth receptors and worked in normal skin but not in skin cancer cells.