Androgen Resistance Associated With a Qualitative Abnormality of the Androgen Receptor and Responsive to High Dose Androgen Therapy

    March 1989 in “ The Journal of Clinical Endocrinology & Metabolism ”
    Placido B. Grino, ROSARIO F. ISIDRO-GUTIERREZ, James E. Griffin, Jean D. Wilson
    TLDR High-dose androgen therapy can help manage certain types of androgen resistance.
    The study investigated a case of androgen resistance due to a qualitative abnormality in the androgen receptor. The patient exhibited symptoms of androgen insensitivity but responded positively to high-dose androgen therapy. This finding suggested that certain forms of androgen resistance could be managed with increased androgen doses, highlighting the potential for tailored therapeutic approaches in similar cases.
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