27 citations
,
January 2001 in “Hormone Research in Paediatrics”
This study found that a lower maintenance dose of flutamide (125 mg/day) effectively maintained the reduction in hirsutism achieved with an initial higher dose (250 mg/day) in women, without additional side effects.
This study found that ethinylestradiol and high-dose cyproterone acetate significantly reduced hirsutism scores and were effective for treating acne and alopecia in women with hyperandrogenism.
88 citations
,
June 2016 in “Human Reproduction Update”
This review discusses developments in oral contraceptives, highlighting improved individualization, reduced side effects, and enhanced suitability for various women's health needs, but it reports no new clinical results.
Dutasteride and high-dose Minoxidil are the primary treatments maintaining hair, with additional supplements and therapies like red light offering minimal extra benefit. The discussion criticizes promoting expensive hair care products when basic medications are doing most of the work.
The conversation discusses the potential for high doses of dutasteride to completely inhibit scalp DHT and speculates whether this could cure baldness when combined with a topical antiandrogen. Specific dosages mentioned are 0.5 mg reducing scalp DHT by 55% and 2.5 mg by about 79%.
Spironolactone, finasteride, and dutasteride are discussed for hair maintenance, with concerns about testosterone and side effects like gynecomastia. Spironolactone is noted for use in both bodybuilding and hormone therapy, with low doses considered for minimizing side effects.
A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.
The conversation discusses various treatments for hair loss, including high doses of dutasteride, oral minoxidil, RU58841, microneedling, ketoconazole shampoo, and other supplements like pumpkin seed oil and multivitamins. It also touches on more extreme measures like estrogen therapy and castration, with some users emphasizing the importance of overall health and nutrition.