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Understanding how acne develops in different diseases could lead to new treatments.

Spironolactone reduces the number of androgen receptor sites in rat skin by blocking them with its metabolite.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Researchers identified genes and proteins that may influence wool thickness in sheep.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

KATP channels are important for energy balance and are targeted by drugs for diabetes, hypoglycemia, hypertension, and hair loss.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Bolandiol, a synthetic steroid, builds muscle and bone without greatly affecting sex glands, and works differently from other hormones.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Mutations in certain receptors can cause diseases and offer new treatment options.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Finasteride may improve prostate cancer treatment outcomes.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

People with hair loss have more androgen receptors and enzymes in certain follicles, with men and women showing different patterns.

Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Fluridil promotes hair growth safely and effectively for androgenetic alopecia.

The Hairless gene is crucial for healthy skin and hair growth.

KGF and its receptor are found in enlarged prostate tissue and KGF strongly increases cell growth.

The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.