31 citations
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August 2021 in “Stem Cell Research & Therapy” This review examines the life cycle, biomarkers, and functions of hair follicle stem cells, emphasizing their role in hair loss therapy and other skin and hair disorders, but reports no new clinical results.
April 2025 in “Cosmetics” In this study, synthesized composite nanocarriers containing ribose and peptides demonstrated enhanced transdermal delivery, improved uptake by skin cells, promoted cell proliferation, enhanced antioxidant enzyme activities, and increased autophagy, suggesting a potential for more effective skin anti-aging treatments.
December 2015 in “Revista Chilena de Dermatología” This article discusses the dermatological manifestations of polycystic ovary syndrome and emphasizes the importance of recognizing acne, hirsutism, and alopecia for early diagnosis; it reports no new clinical results.
6 citations
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May 2020 in “Pharmacology Research & Perspectives” This study in rats found that a new hydroxypropyl-β-cyclodextrin formulation of minoxidil reduced the adverse cardiovascular and proliferative effects seen with traditional minoxidil solutions.
13 citations
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July 2024 in “Heart Failure Reviews” This review compiles data on how the apelinergic system may protect against heart damage caused by doxorubicin cancer treatment, suggesting its potential to mitigate cardiotoxicity, though further research in chronic models is needed to confirm these effects and mechanisms.
142 citations
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December 1991 in “Antimicrobial Agents and Chemotherapy” This study reported that continuous intravenous dextran sulfate was toxic and ineffective as a treatment for symptomatic HIV infection, as it did not improve surrogate markers and caused significant side effects.
48 citations
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July 1992 in “International Journal of Dermatology” HIV can cause various nail and hair disorders, important for early diagnosis and treatment.
43 citations
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November 2007 in “Journal of Investigative Dermatology Symposium Proceedings” This paper reviews symptoms, causes, and treatment strategies for common scalp conditions such as dandruff and psoriasis, but does not present new clinical findings.
42 citations
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January 2007 in “Pediatric dermatology” This report describes an 11-year-old boy with Netherton syndrome who developed Cushing syndrome after using low-potency hydrocortisone ointment extensively, highlighting caution with long-term topical treatments in such conditions.
38 citations
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February 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This report describes two cases of sustained hair repigmentation related to porphyria cutanea tarda, though the underlying mechanism remains unclear.
26 citations
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October 2011 in “International Journal of Biological Macromolecules” This study found that some synthesized heterocyclic derivatives showed promising 5α-reductase inhibitor, antiviral, and anti-tumor activities, surpassing several reference drugs in effectiveness.
25 citations
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June 2021 in “Developmental Cell” In this study, researchers found that deleting Caspase-9 in hair follicle stem cells delayed apoptosis, leading to accelerated wound repair and new hair follicle regeneration by maintaining apoptotic cells as signaling centers.
20 citations
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September 2015 in “Protein expression and purification” This study demonstrated that safflower seeds can be engineered to express oleosin-FGF10, which showed a dose-dependent effect on cellular proliferation, potentially facilitating scalable protein production.
14 citations
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May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
12 citations
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May 2001 in “British journal of dermatology/British journal of dermatology, Supplement” A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.
9 citations
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April 2019 in “Journal of structural biology” This study found that coconut oil impedes hair hydration more effectively than soybean oil by penetrating deeper, and suggested a new model for intermediate filament assembly in hair.
6 citations
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January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This study found that topical application of triiodothyronine (T3) can induce the transition of hair follicles from the telogen to the anagen phase in mice and stimulate hair shaft growth in vitro.
3 citations
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January 1996 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” In this study, a 33-year-old HIV-infected man experienced alopecia areata after beginning zidovudine therapy, which reversed upon discontinuation.
3 citations
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August 2023 in “World Journal of Biology and Biotechnology” This research underscores the critical role of the human microbiome in health, highlighting potential therapeutic benefits of interventions like fecal microbiota transplantation and probiotics for conditions linked to microbiome dysbiosis, such as metabolic disorders and inflammatory diseases.
2 citations
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January 2021 in “Signa Vitae” This study found that COVID-19 patients discharged from the San Cecilio University Hospital during the first pandemic wave frequently returned to the ED, with thoracic pain and general malaise identified as significant risk factors for readmission.
1 citations
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February 2022 in “Open Access Macedonian Journal of Medical Sciences” This study found that lower zinc serum levels may contribute to premature hair graying in college students at Universitas Sumatera Utara.
1 citations
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April 2021 in “International Journal of Dermatology” This review discusses the relationship between hyperandrogenic conditions like PCOS and COVID-19, noting that while hyperandrogenic women have varied hospitalization rates, they do not show increased mortality, and suggests isotretinoin as a potential therapeutic option for cutaneous symptoms.
1 citations
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May 2019 in “British journal of health care management/British journal of healthcare management” This study highlighted the critical role emollients play in managing dry skin conditions and reported that prescribing suitable emollient therapy may reduce overall healthcare costs and the need for additional medications in UK primary care.
July 2023 in “Media Dermato Venereologica Indonesiana” This research discusses Stevens-Johnson syndrome and toxic epidermal necrolysis, life-threatening conditions often induced by immune-mediated drug reactions. Optimal management involves early diagnosis, drug withdrawal, and supportive therapy, though evidence for systemic treatments like corticosteroids and cyclosporin remains variable and lacks randomized controlled trial confirmation.
September 2021 in “Revista Interdisciplinar em Saúde” In this observational study, treatment with oral isotretinoin was reported to stabilize hair loss in patients with frontal fibrosing alopecia, offering potential guidance for clinicians on its therapeutic use, with implications for improving affected patients' self-esteem.
September 2021 in “Revista interdisciplinar em saúde” This study reported that oral isotretinoin effectively stabilized frontal fibrosing alopecia in patients, which may help guide healthcare providers in managing this condition related to hair loss and self-esteem.
March 2026 in “American Journal of Clinical Dermatology” This narrative review provides an overview of the persistent dermatological side effects experienced by cancer survivors due to treatments, highlighting their impact on quality of life and the need for structured dermatological care during survivorship.
October 2025 in “Open Repository of the University of Porto (University of Porto)” In this report, the author summarized activities from a six-month internship in community and hospital pharmacy settings, exploring topics like skin microbiome health implications and advancements in antiviral therapy for Hepatitis B and D, highlighting the pharmacist's role in patient care and innovative treatments.
This study reviewed the etiology, mechanisms, and treatments of scarring alopecias and noted that early and accurate identification is crucial due to overlapping features among different types, making differential diagnosis challenging.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that disrupted cholesterol homeostasis impairs hair regrowth in individuals with primary cicatricial alopecia by damaging hair follicle stem cells, highlighting the importance of cholesterol in maintaining stem cell function and hair follicle integrity.