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Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Curcumin may improve blood sugar levels and cholesterol in people with PCOS, but more research is needed.

Stress in mice delays hair growth and treatments blocking substance P can partly reverse this effect.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

Thyroid diseases may contribute to autoimmune skin diseases, and more research is needed on their relationship.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Coriander seed oil is safe for healthy adults at up to 600 mg per day.

High fasting insulin levels in women with PCOS are linked to a higher risk of heart and metabolic problems.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.

Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

The proteins transthyretin and megalin are more present in the growth phase of hair, suggesting they might affect hair health and growth.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Melatonin receptors, found in many body parts, can help treat various diseases like depression and diabetes due to their effects on inflammation, tumor progression, sleep disorders, and body mass regulation.

5-alpha reductase inhibitors can cause sexual, neurologic, endocrine, and cardiovascular side effects, but these are rare and usually stop after ending treatment.