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The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

Thyroid hormones help hair grow, reduce hair loss, and increase hair pigment.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.

New treatments for male hypogonadism are effective and should be personalized.

Targeting the skin's endocannabinoid system could help treat skin disorders.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Using finasteride or dutasteride may cause long-lasting erectile dysfunction.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Eating healthy, exercising, and taking certain supplements can help manage Polycystic Ovary Syndrome symptoms.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Melatonin improved mental health and metabolism in women with PCOS.