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This study found that adipocytes in the interfacial white adipose tissue adjacent to fibrotic lesions in systemic sclerosis show unique phenotypes and contribute to the condition's pathogenesis.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

In this study, a subcutaneous injection of recombinant RSPO1 was found to activate hair follicle stem cells and enhance hair regeneration in mice by stimulating the Wnt/β-catenin signaling pathway, suggesting its potential as a treatment for hair loss.

This study found that administering human amniotic mesenchymal stem cells (hAMSCs) in a mouse model of psoriasis improved skin lesions and reduced inflammation-related markers, suggesting potential therapeutic benefit and safety for treating psoriasis, and identified specific gene targets involved in the treatment's mechanism.

This clinical letter identifies Rothmund-Thomson syndrome type 2 as a rare cause of chronic wounds, but provides no new experimental findings.

In this study, researchers developed a new SFL-3D system to produce extracellular vesicles from rejuvenated dermal papilla cell spheroids, which demonstrated significant antifibrotic effects in reducing hypertrophic scarring, highlighting their potential for precision-targeted scar management.

This review discusses the roles of tissue-specific and mesenchymal stromal cells in tissue repair and reparative disorders, highlighting potential therapeutic targets for muscle, heart, and lung tissues.

Subcision is the most efficient, cost-effective, and safest treatment for post-acne boxcar scarring in skin of color.

This rat study found that a PLGA conduit filled with neural crest stem cells derived from hair follicles showed promising results in repairing peripheral nerve injuries, partially restoring sensory function and improving nerve structure.

In this study, transplantation of rat hair follicle stem cells was associated with reduced infarct volume and enhanced neurological recovery after ischaemic stroke, suggesting therapeutic potential for further clinical development.

Hair follicle stem cells may help repair the brain after a stroke.

The researchers identified a pathogenic variant in the SRD5A2 gene among siblings with 46,XY disorder of sexual development, highlighting the importance of comprehensive genetic testing in diagnosis and management.

This study found that intracrine androgen signaling via 5α-reductase is essential for optimal endometrial decidualization and vascular development during this process in mice.

Researchers created a new mouse model for studying scleroderma.

This paper discusses the potential roles of adipose tissue derived stem cells in skin regeneration and wound healing but emphasizes the need for further research on their effectiveness in clinical settings.

This review discusses central serous chorioretinopathy, detailing its etiology, associated factors, diagnostic imaging, and therapeutic options, but provides no new clinical findings.

This review evaluated the potential of adipose-derived stem cells (ADSCs) for burn treatment, finding promising regenerative healing effects, though most findings are at early experimental stages primarily in animal models.

In laboratory models of human skin, this study found that treating with resveratrol significantly increased glutathione levels, potentially enhancing the skin's antioxidant defenses.

This review discusses current experimental research on the use of stem cells, particularly ADSCs and BM-MSCs, in plastic and reconstructive surgery but reports no new clinical findings.

This review discusses the diagnosis and management of severe cutaneous adverse reactions to drugs and provides guidance for physicians to improve patient outcomes, but it reports no new clinical results.

This study found that combining platelet-rich plasma with adipose-derived mesenchymal stem cells significantly improved diabetic wound healing in rats by enhancing angiogenesis and modulating the Notch signaling pathway.

In this study, Nrf-2-expressing hair follicle mesenchymal stem cells showed the most significant therapeutic effect in a rat model of ulcerative colitis, suggesting a new potential treatment for the disease.

This study found that fibroblasts play a crucial role in scar formation during dermal development and identified N-Cadherin as a key molecule in their response, suggesting new therapeutic avenues for scar prevention.

This study found that forming spheroids using silicone micro-wells improved the viability and neural differentiation potential of human adipose-derived stem cells after thawing.

This study identified a novel mechanism by which dsRNA-induced TLR3 activation and retinoic acid pathways contribute to new hair follicle formation after deep wounds in mice and suggested a similar potential in humans.

This study found that a cell therapy product, RCS-01, was well tolerated in aged skin and led to significant increases in gene expression related to extracellular matrix homeostasis, although the small cohort size limited further efficacy analysis.

The researchers reported that sulfated chitosan-containing sponges can modulate macrophage activity in diabetic wounds, reducing inflammation and promoting angiogenesis and tissue regeneration, which may enhance wound healing outcomes.

In this study, R-CSLM showed promise in evaluating hair shaft diseases by providing high-quality images of hair structures, although further development is necessary for follicle and perifollicular area analysis.

This study suggested that non-colony dissociated hiPSCs can be effectively differentiated into functional RPE cells, and hiPSC-RPE cell spheroids showed promise for use in subretinal transplantation in animal models of retinal degeneration.

This study detected sarcoptic mange in five free-ranging raccoon dogs in Schleswig-Holstein, Germany, with four showing severe skin lesions and potential secondary bacterial infections, suggesting they may act as vectors in disease spread.