Amelioration of Psoriasis-Like Skin Lesions by Human Amniotic Mesenchymal Stem Cells: Insights from Multiomics Profiling in Mice

    February 2026 in “ Frontiers in Immunology ”
    Liehao Yang, Baihui Miao, Qian Sun, Fangqing Zhang, Hongyan Sun, Zilong Zhou, Yue Hu, Zhiming Cui, D. Y. Wang, Chenlu Liu, Liang Zhang, Qianying Hu, Xianling Cong
    TLDR Human amniotic stem cells can safely treat psoriasis-like skin in mice.
    The study demonstrates that human amniotic mesenchymal stem cells (hAMSCs) are effective and safe for treating psoriasis-like skin lesions in mice. Through multiomics profiling, the research provides insights into the mechanisms by which hAMSCs exert their therapeutic effects, confirming their potential as a treatment option for psoriasis.
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