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    Glossary Radiation Damage

    ionizing radiation harms living tissues, causing DNA mutations and cell death

    Radiation Damage, also known as Radiation Injury, refers to the harmful effects that ionizing radiation can have on living tissues. This damage can occur at the cellular level, leading to DNA mutations, cell death, and impaired tissue function. In the context of hair, radiation damage can result in hair loss (alopecia) due to the destruction of hair follicle cells.

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    1. Effect of antioxidant supplementation on digestive enzymes in radiation induced intestinal damage in rats International Journal of Radiation Biology · 2013 · 22 citations
    2. Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation Proceedings of the National Academy of Sciences of the United States of America · 2007 · 184 citations
    3. Damage of hair follicle stem cells and alteration of keratin expression in external radiation-induced acute alopecia International Journal of Molecular Medicine · 2012 · 28 citations
    4. Impact of ultraviolet radiation‐induced damage to hair fiber integrity: A multi‐technique physicochemical characterization of surface and cortex properties International Journal of Cosmetic Science · 2026
    5. 910 Transepidermal UV radiation of human scalp skin induces distinctive hair follicle damage, which is mitigated by topical caffeine treatment Journal of Investigative Dermatology · 2019
    6. Keratin 17 Impacts Global Gene Expression and Controls G2/M Cell Cycle Transition in Ionizing Radiation–Induced Skin Damage 2023 · 3 citations
    7. Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 1 citations
    8. The Ethnic Differences of the Damage of Hair and Integral Hair Lipid after Ultra Violet Radiation Annals of Dermatology · 2013 · 59 citations
    9. Transepidermal UV radiation of scalp skin <i>ex vivo</i> induces hair follicle damage that is alleviated by the topical treatment with caffeine International Journal of Cosmetic Science · 2019 · 31 citations
    10. Author response: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage 2021
    11. Editor's evaluation: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage 2021
    12. Measuring oxidative damage to human hair from solar radiation and pollution: A critical review Journal of Photochemistry and Photobiology · 2026
    13. 287 Mackerel fermented fish oil suppresses human keratinocyte damage caused by ultraviolet B radiation Journal of Investigative Dermatology · 2017
    14. Porcine skin damage thresholds and histological damage characteristics from 1319-nm laser radiation Journal of Biomedical Optics · 2019 · 5 citations
    15. Cell and Tissue Damage after Skin Exposure to Ionizing Radiation: Short- and Long-Term Effects after a Single and Fractional Doses Cells Tissues Organs · 2014 · 14 citations
    16. 837 From genotoxic stresses to skin damage: Distinct, novel mechanisms of skin and hair damage in chemo/radiation therapy Journal of Investigative Dermatology · 2017
    17. Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3 Cancer Research · 2007 · 76 citations
    18. Decision letter: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage 2021
    19. ToF‐SIMS characterization of the lipid layer on the hair surface. I: the damage caused by chemical treatments and UV radiation Surface and interface analysis · 2010 · 23 citations
    20. Adipose-derived stem cells alleviate radiation-induced dermatitis by suppressing apoptosis and downregulating cathepsin F expression Stem Cell Research & Therapy · 2021 · 50 citations
    21. Establishment and characterization of a radiation‐induced dermatitis rat model Journal of Cellular and Molecular Medicine · 2019 · 16 citations
    22. The preventive effect of vitamin D3 on radiation-induced hair toxicity in a rat model Life sciences · 2005 · 14 citations
    23. Activation of mTORC1 Signaling is Required for Timely Hair Follicle Regeneration from Radiation Injury Radiation Research · 2017 · 12 citations
    24. FGF signaling for hair cycle resting phase alleviates radiation alopecia Journal of Dermatological Science · 2016 · 1 citations
    25. Radiation Dermatitis: Radiation-Induced Effects on the Structural and Immunological Barrier Function of the Epidermis International journal of molecular sciences · 2024 · 1 citations
    26. Pediatric Radiation-Induced Alopecia Post Intracranial Vascular Malformation Embolization: A Case Report with Dermoscopic Findings Clinical Cosmetic and Investigational Dermatology · 2026
    27. Caffeine ameliorates radiation-induced skin reactions in mice but does not influence tumour radiation response Journal of Radiological Protection · 2002 · 35 citations
    28. Biochemical and Histopathological Evaluation of the Radioprotective Effects of Melatonin Against Gamma Ray-Induced Skin Damage Current radiopharmaceuticals · 2018 · 15 citations
    29. Radiation-Induced Microvascular Injury as a Mechanism of Salivary Gland Hypofunction and Potential Target for Radioprotectors Radiation Research · 2016 · 41 citations
    30. Brain and muscle Arnt-like protein-1 (BMAL1) controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012 · 221 citations