Does Active Form of Vitamin D3 Prevent Hair Follicles from Radiation Toxicity?

October 2004 in “ Radiotherapy and oncology ”

calcitriol vitamin D3 radiation toxicity hair follicles dermal atrophy radiation-induced hair loss active form of vitamin D3

TLDR Active vitamin D3 might protect hair follicles from radiation damage.

The study from 2004 investigated the protective effects of calcitriol, the active form of vitamin D3, on hair follicles against radiation toxicity in rats. It involved three groups: Group I (7 rats) received radiation only, Group II (7 rats) received calcitriol before radiation, and a control group (5 rats) received no radiation. Results indicated that Group II rats did not show a significant difference in the number of hair follicles between irradiated and non-irradiated skin, unlike Group I. Despite dermal atrophy in both irradiated groups, the study concluded that calcitriol may protect hair follicles from radiation toxicity, suggesting it could prevent radiation-induced hair loss, but emphasized the need for further trials.

View this study on thegreenjournal.com →

Discuss this study in the Community →

Similar Research

5 / 562 results

research Study of Gene Expression Alteration in Male Androgenetic Alopecia: Evidence of Predominant Molecular Signaling Pathways

27 citations, April 2017 in “British Journal of Dermatology”

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

research Vitamin D and Skin: A Review and Update

April 2024 in “Nepal journal of dermatology, venereology & leprology”

Vitamin D is important for skin health and can help treat and prevent various skin conditions.

research Dissecting the Impact of Chemotherapy on the Human Hair Follicle

99 citations, September 2007 in “The American journal of pathology”

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

research Pathobiology of Chemotherapy-Induced Hair Loss

218 citations, January 2013 in “The Lancet Oncology”

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

research Topical L-Thyroxine: The Cinderella Among Hormones Waiting to Dance on the Floor of Dermatological Therapy?

9 citations, July 2020 in “Experimental Dermatology”

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Does Active Form of Vitamin D3 Prevent Hair Follicles from Radiation Toxicity?

Related Community Posts Join

community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

community Using topical vitamin D, does it make sense?

community 8mg on oral finasteride. No results?

community One year of progress (Fin, 1mg)

community I bought a microscope, how does my scalp/hairs look? I've been suffering diffuse thinning and hair loss after covid and never recovered (2 yrs ago) I eat healthy, in shape and workout.