A Simple Assay for the Study of Human Hair Follicle Damage Induced by Ionizing Irradiation

    November 2009 in “ Experimental dermatology ”
    Burkhard Pöeggeler, Enikő Bodó, Roger Nadrowitz … Ralf Paus
    Studysummary This study found that ionizing irradiation significantly inhibits proliferation and induces apoptosis in human hair follicle keratinocytes, suggesting its potential as a preclinical assay system for testing radioprotectants.
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    Research cited in this study 11

    1. The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
    2. Profiling the Response of Human Hair Follicles to Ultraviolet Radiation Journal of Investigative Dermatology · 2009
    3. Modulation of Chemotherapy-Induced Human Hair Follicle Damage by 17-Beta Estradiol and Prednisolone: Potential Stimulators of Normal Hair Regrowth by Dystrophic Catagen Promotion? Journal of Investigative Dermatology · 2008
    4. Dissecting the Impact of Chemotherapy on the Human Hair Follicle ˜The œAmerican journal of pathology · 2007
    5. Expression of the Human Cathepsin L Inhibitor Hurpin in Mice: Skin Alterations and Increased Carcinogenesis Experimental Dermatology · 2007
    6. Therapeutic Strategies for Treating Hair Loss Drug Discovery Today: Therapeutic Strategies · 2006
    7. The Preventive Effect of Vitamin D3 on Radiation-Induced Hair Toxicity in a Rat Model Life sciences · 2005
    8. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005
    9. A Phase I Study of Topical Tempol for the Prevention of Alopecia Induced by Whole Brain Radiotherapy Clinical Cancer Research · 2004
    10. Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)? ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 1998
    11. Human Hair Growth In Vitro Journal of Cell Science · 1990

    Related research 3

    1. Hair Growth Promoting Effect of Urtica Dioica L Central Asian journal of medical sciences (Print) · 2018
    2. Human Hair Growth Ex Vivo Is Correlated With In Vivo Hair Growth: Selective Categorization of Hair Follicles for More Reliable Hair Follicle Organ Culture Archives of Dermatological Research · 2005
    3. Reorganization of Hair Follicles in Human Skin Organ Culture Induced by Cultured Human Follicle-Derived Cells Experimental Dermatology · 2005