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Clinicians should look for skin issues, sleep problems, cognitive changes, and food cravings as signs of insulin resistance.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

People with alopecia areata have higher insulin resistance.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Obesity is linked to skin conditions like acanthosis nigricans and skin tags, which may indicate high insulin levels.

Women with PCOS and polycystic ovaries have higher male hormone levels and more insulin resistance, especially if they are overweight.

Metformin and rosiglitazone both improved insulin use and hormonal symptoms in women with PCOS.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

Both treatments reduced excessive hair growth in PCOS, but there was no difference in weight, hair score, hormone levels, or insulin resistance.

Knuckle Acanthosis Nigricans is common in Latin American youth and may indicate early insulin resistance, especially in those with normal weight.

Hypothyroidism may worsen metabolic problems like insulin resistance and obesity in women with PCOS.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Changing the diagnosis criteria for PCOS might miss women at risk for related health issues.

STK11 gene variations do not predict how well metformin will work for PCOS, but may affect hair loss and excess hair growth.

Eating a high inositol diet significantly improves insulin resistance and hormone levels in women with PCOS.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

People with alopecia are at higher risk for heart disease and have more heart-related risk factors.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Polycystic ovary syndrome is a common hormonal disorder in women, linked to increased risk of metabolic and heart diseases, and needs more research for better understanding and treatment.

Hair loss may indicate higher heart risk and metabolic issues.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

Children with classic congenital adrenal hyperplasia have thicker heart fat and are at higher risk for heart problems and early atherosclerosis.