In this study, metformin, pioglitazone, and ethinylestradiol cyproterone all improved various clinical features and quality of life in Pakistani women with PCOS, though no drug significantly reduced hirsutism.
1 citations
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January 2017 in “Endokrynologia Pediatryczna” This review concludes that polycystic ovary syndrome can significantly impact aspects of health-related quality of life in adolescent girls, especially body image and interpersonal functioning.
April 2026 in “Journal of Dermatological Treatment” This study concluded that in female pattern hair loss patients, CGF and i-PRF treatments were more effective than PRP in increasing target area hair count, with i-PRF having the lowest adverse event rate.
October 2019 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that the developed hydrogel nanoparticles showed potential for enhancing hair growth by effectively delivering and releasing hair growth-promoting herbal extracts into hair follicles.
11 citations
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July 2021 in “Physiologia Plantarum” In this study, the gene SlPHL1 was identified as a transcription factor in tomatoes that enhances phosphate starvation responses by upregulating specific genes.
October 2025 in “Dermatology Practical & Conceptual” This study found that ChatGPT 4.0 and Gemini 1.5 Flash provided more accurate and user-friendly responses to androgenetic alopecia questions than Deepseek R1, suggesting they could be effective tools for patient education with physician guidance.
1 citations
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November 2024 in “Blood” This study found that inhibiting the PI3Kδ enzyme in murine models of cutaneous chronic graft-versus-host disease (cGVHD) reduced skin scores and fibrosis, prevented pathogenic lymphoid structures, and improved survival, suggesting it as a promising therapeutic approach to address the disease's hypoxic pathophysiology.
1 citations
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August 2025 This study found that GLP-1 receptor agonists show potential for improving psoriasis and hidradenitis suppurativa by reducing inflammation and lesion severity, but they also pose dermatological risks such as alopecia and injection site reactions.
15 citations
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August 2022 in “Daehan saengsik uihak hoeji/Clinical and experimental reproductive medicine” This pilot study found that intraovarian platelet-rich plasma administration significantly improved the euploidy rate of embryos in infertile women with previous IVF failures.
December 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” This study revealed that Patched receptors establish a Hedgehog signaling gradient in developing hair follicles, which may influence their formation and potentially offer a diagnostic tool for distinguishing Hedgehog-driven tumors.
22 citations
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September 2022 in “Journal of Animal Science” This study suggests that the PI3K-AKT signaling pathway may significantly influence the development of different hair types in Inner Mongolia cashmere goats.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that a proteomics-based approach can effectively distinguish between scalp and pubic hair by identifying unique protein signatures, providing a more quantitative and objective method for tracing hair contamination sources in GMP manufacturing and forensic investigations.
This review highlights concerns about dermatological side effects linked to rapid weight loss from glucagon-like peptide-1 receptor agonists used for type 2 diabetes and obesity treatment, such as skin laxity, decreased collagen, and hair loss, emphasizing the importance of managing these while retaining metabolic benefits.
September 2025 in “Cureus” This review suggests that GLP-1 receptor agonists may improve various dermatologic conditions, but larger studies are needed to confirm these findings.
2 citations
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January 2007 in “Acta Dermato Venereologica” In this report, a case of a bullous lesion developed at the injection site in a patient treated with PEG-IFN-α-2a for chronic hepatitis C was described.
2 citations
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May 2017 in “International journal of pharmacy and pharmaceutical sciences/International Journal of Pharmacy and Pharmaceutical Sciences” This review discusses genetic mutations associated with Hutchinson-Gilford progeria syndrome and reports no clinical results; the authors emphasize the importance of cardiovascular monitoring in management.
29 citations
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November 2011 in “Human Fertility” This study reports significant variability in PCOS symptoms across women attending infertility, gynecology, endocrine, and dermatology clinics, highlighting the importance of recognizing diverse presentations and associated health risks like impaired glucose tolerance and diabetes.
October 2021 in “JAAD Case Reports” This article discusses diabetic gustatory hyperhidrosis as a rare form of autonomic dysfunction linked to severe diabetic neuropathy and nephropathy, noting its impact on social and emotional well-being.
March 2022 in “Benha Journal of Applied Sciences” This study found that serum PGRN levels and HOMA-IR were significantly higher in male AGA patients compared to controls, suggesting a link to insulin resistance and metabolic syndrome.
January 1990 in “UCL Discovery (University College London)” This study found that guinea pig α-lactalbumin transgene was expressed in the mammary glands and sebaceous glands of transgenic mice, with milk protein production occurring in the expected secretory acini.
1 citations
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November 2022 in “Experimental cell research” This study found that a PGE2 matrix, when injected subcutaneously, increased the proportion of developing hair follicles and improved hair follicle stem cell markers in a mouse model of hair loss.
This source explains that Equine Cushing’s disease, or PPID, in horses is due to the degeneration of brain cells producing dopamine, leading to elevated cortisol levels and characteristic symptoms; it outlines diagnosis methods and emphasizes life-long pergolide treatment to manage the condition.
May 2024 in “JAAD Case Reports” This case report describes a 29-year-old man with a year-long non-itchy skin eruption and hair loss, with distinct papules and plaques across his scalp, beard, body, and suprapubic regions, but no systemic symptoms or family history of autoimmune disease.
102 citations
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July 2007 in “Genes & Development” This study found that maternal PPARγ is essential for preventing the production of inflammatory lipids in mouse milk, which can otherwise cause inflammation, alopecia, and growth retardation in nursing pups.
1 citations
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October 2022 in “Current Opinion in Endocrinology, Diabetes and Obesity” This review discusses the diagnosis, management, and clinical challenges of female pattern hair loss in PCOS patients but reports no new clinical findings, highlighting the need for further research and multidisciplinary care.
This study found that GPC1 is a significant regulator of angiogenesis in human dermal microvascular endothelial cells, suggesting its potential as a target for alopecia research.
January 2024 in “Wiadomości Lekarskie” This source analyzes linguistic difficulties faced by speakers of East Slavic languages learning Polish, emphasizing challenges in pronunciation, vocabulary, and grammar. It suggests that tailored educational materials comparing linguistic nuances can improve learning outcomes by highlighting important differences between the languages.
June 2022 in “Indian journal of clinical and experimental opthalmology” This case report details the ocular complications of Hutchinson-Gilford Progeria syndrome in a 20-year-old Bangladeshi patient, highlighting symptoms like dry eyes, Meibomian gland dysfunction, and cataracts.
April 2020 in “Journal of the Endocrine Society” This case report describes a 34-year-old woman with pituitary stalk interruption syndrome, highlighting the need for long-term follow-up due to potential progression from isolated hormonal deficiencies to pan-hypopituitarism.
7 citations
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December 2008 in “Journal of Dermatological Science” Progranulin overexpression leads to shorter, thinner hair and increased cell death in mouse hair follicles.