Bullous Lesions at Polyethylene Glycol Interferon-Alpha-2a Inoculation Site in a Hepatitis C Virus-Infected Subject

    January 2007 in “ Acta Dermato Venereologica ”
    MA Montesu, V Siddi, Rosanna Satta, C Pirodda, Francesca Cottoni
    TLDR A patient developed a blister at the injection site after hepatitis C treatment.
    A patient with chronic hepatitis C virus (HCV) infection developed a bullous lesion at the inoculation site after treatment with polyethylene glycol interferon-alpha-2a (PEG-IFN-α-2a). This case added to the known dermatological side effects of PEG-IFN, which included both widespread issues like hair loss, pruritus, and vitiligo, and localized issues such as cutaneous ulcerations and necrosis.
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