research Treatment of Cystathionine Beta-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector
MC-DNA vector-based gene therapy can temporarily treat CBS deficiency in mice.
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research Signal Transducer and Activator of Transcription 5B Deficiency Due to a Novel Missense Mutation in the Coiled-Coil Domain
A boy's growth and immune problems were caused by a new mutation in the STAT5B gene.
research Effects of Topical Application of EGCG on Testosterone-Induced Hair Loss in a Mouse Model
Applying EGCG on the skin can prevent hair loss caused by testosterone in mice.
research In Vivo Investigation in Pigs of Intestinal Absorption, Hepatobiliary Disposition, and Metabolism of the 5α-Reductase Inhibitor Finasteride and the Effects of Coadministered Ketoconazole
Ketoconazole increases finasteride's effectiveness and lifespan in the body.
research A Connection Between the Mitochondrial Permeability Transition Pore, Autophagy, and Cerebral Amyloidogenesis
Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.
research An Intrafamilial Transmission of Arthroderma Benhamiae in Canadian Porcupines (Erethizon Dorsatum) in a Japanese Zoo
Canadian porcupines in a Japanese zoo passed a skin fungus to each other.
research Dopa Oxidase Activity in Hair, Skin, and Ocular Melanocytes Is Increased in the Presence of Stressed Fibroblasts
Stressed fibroblasts greatly increase melanin production in hair, skin, and eye cells, mainly due to a growth factor called bFGF.
research Gene Expression in Rat Dermal Papilla Cells: Analysis of 2529 ESTs
Rat dermal papilla cells have unique genes crucial for hair growth.
research 3,4,5-Tri-O-Caffeoylquinic Acid Promoted Hair Pigmentation Through β-Catenin and Its Target Genes
A substance called TCQA could potentially darken hair by activating certain genes and increasing melanin.
research CRISPR/Cas9-Mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen
Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Ethyl Acetate Fraction of Eclipta Alba: A Potential Phytopharmaceutical Targeting Adipocyte Differentiation
Eclipta alba extract may help treat obesity by blocking fat cell formation and lowering blood lipid levels.
research Hair Growth Promoting and Anticancer Effects of p21-Activated Kinase 1 (PAK1) Inhibitors Isolated from Different Parts of Alpinia Zerumbet
Compounds from Alpinia zerumbet may help with hair regrowth and cancer treatment by targeting PAK1.
research Identification of a Cyclosporine-Specific P450 Hydroxylase Gene Through Targeted Cytochrome P450 Complement Disruption in Sebekia Benihana
A gene in Sebekia benihana, CYP-sb21, is needed for a specific reaction on the drug Cyclosporine A, which could be important for hair growth without affecting the immune system.
research Nanocarrier Systems for Transdermal Drug Delivery
Nanocarriers could improve how drugs are delivered through the skin but require more research to overcome challenges and ensure safety.
research Modulation of the 6-Position of Benzopyran Derivatives and Inhibitory Effects on the Insulin Releasing Process
Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.
research Development and Evaluation of Antisense shRNA-Encoding Plasmid Loaded Solid Lipid Nanoparticles Against 5-Alpha Reductase Activity
The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.
research Evaluating the Antioxidant Effects of Human Hair Protein Extracts
Human hair protein extracts can protect skin cells from oxidative stress.
research Analysis of Changes in MicroRNA Expression Profiles in Response to the Troxerutin-Mediated Antioxidant Effect in Human Dermal Papilla Cells
Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.
research Mouse Hair Cycle Expression Dynamics Modeled as Coupled Mesenchymal and Epithelial Oscillators
The study concluded that hair growth in mice is regulated by a stable interaction between skin cell types, and disrupting this can cause hair loss.
research Characterization of Hair Lipid Images by Argon Sputter Etching-Scanning Electron Microscopy
Hair texture changes with age due to varying levels of lipids.
![Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1](/images/research/c687900f-ea40-4de1-8f0b-a5b818951b1c/small/15452.jpg)
research Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5α-Reductase 1
Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.
research Structure and Hair Follicle-Specific Expression of Genes Encoding the Rat High Sulfur Protein B2 Family
The B2 genes are crucial for hair growth in rats.
research Controlled Release of the Alpha-Tocopherol-Derived Metabolite Alpha-13'-Carboxychromanol from Bacterial Nanocellulose Wound Cover Improves Wound Healing
Wound covers with α-13'-COOH from vitamin E can improve and speed up wound healing.
research Current Status of Genus Impatiens: Bioactive Compounds and Natural Pigments with Health Benefits
Impatiens plants have health-promoting compounds and are used for natural food coloring, but more research is needed to understand their full benefits.
research Oil Body-Bound Oleosin-rhFGF-10: A Novel Drug Delivery System That Improves Skin Penetration to Accelerate Wound Healing and Hair Growth in Mice
A new drug delivery system using oil body-bound oleosin-rhFGF-10 improves wound healing and hair growth in mice.
research A Functional Polymorphism in Interleukin-1α (IL1A) Gene Is Associated with Risk of Alopecia Areata in Chinese Populations
A certain genetic variation in the IL1A gene may lower the risk of a hair loss condition in Chinese people.
research A Function for Rac1 in the Terminal Differentiation and Pigmentation of Hair
Rac1 is essential for proper hair structure and color.
research Expression of NAD+-Dependent 15-Hydroxyprostaglandin Dehydrogenase and Protection of Prostaglandins in Human Hair Follicle
A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.
research Other Antiandrogens: Alternative Treatments for Acne and Hirsutism
Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.