1 citations
,
July 2021 in “Aesthetic Plastic Surgery” This study concluded that a triangular flag-shaped incision design in hair transplantation achieved better hair alignment compared to the common elliptical incision, particularly in patients with specific hair directions.
20 citations
,
March 1975 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” This study found a direct correlation between the testicular feminization gene and decreased androgen receptor activity, potentially explaining the androgen insensitivity in affected individuals.
27 citations
,
May 2011 in “Journal of Investigative Dermatology” TCHHL1 is a protein important for hair growth, found in hair follicles.
9 citations
,
March 2022 in “Frontiers in Immunology” This review discusses the roles and mechanisms of tissue-resident regulatory T cells in immune regulation and tissue homeostasis, but reports no new experimental results.
August 2024 in “Indian Journal of Dermatology Venereology and Leprology”
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December 2020 in “TURKDERM” This case report describes a 3-year-old boy diagnosed with temporal triangular alopecia, emphasizing the importance of clinical and dermoscopic examination for correct diagnosis due to the condition's rarity and risk of misdiagnosis.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.
148 citations
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October 1997 in “Journal of Investigative Dermatology” TGF-β receptors are crucial for hair follicle development.
37 citations
,
April 2013 in “PLoS ONE” In this study, the researchers found that thymosin beta-4 promotes odontoblastic differentiation in human dental pulp cells, suggesting it as a potential mechanism for regenerative endodontics.
22 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” This study found that resveratrol and fisetin promoted hair growth in mice by inducing telomerase reverse transcriptase expression, which activates hair follicle stem cells and transitions follicles from a resting to a growth phase.
20 citations
,
December 2015 in “Journal of Pharmacopuncture” In this study, thread-embedding therapy enhanced hair regrowth in C57BL/6 mice by regulating growth factors associated with hair follicle anagen development and promoting cellular proliferation in hair follicles.
January 2007 in “대한피부과학회지” In this clinical trial, the topical agent AP-FHG0604T significantly increased hair counts and growth rates in women with female pattern hair loss compared to a placebo, though some reported mild local irritation.
321 citations
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January 2012 in “Cell stem cell” This study identified TGF-β2 as a crucial signal in hair follicle stem cell regeneration, highlighting its role in counteracting BMP signaling to promote tissue regeneration.
10 citations
,
July 2011 in “Wound Repair and Regeneration” This article proposes several potential approaches for scar prevention and therapy, including anti-transforming growth factor-β strategies and tissue-engineered skin, but reports no new clinical results.
November 2024 in “International Society of Hair Restoration Surgery” This treatise provides guidelines and suggestions for the safe practice of follicular unit transplantation but reports no new clinical results.
2 citations
,
June 2020 in “Clinical Journal of Gastroenterology” This case report describes two patients with ulcerative colitis and alopecia areata who did not respond to various treatments but achieved remission and improved hair growth after starting tofacitinib.
2 citations
,
January 2009 in “Human cell culture” January 2025 in “International Journal of Pharmaceutics” In this study, gelatin-coated transferosomes were developed to deliver tofacitinib specifically to hair follicles, resulting in 80% hair regrowth in alopecia areata patients with recalcitrant lesions after 12 weeks of treatment.
3 citations
,
February 2024 in “Journal of the American Academy of Dermatology” This source discusses that while oral JAK inhibitors are used for treating lichen planopilaris and frontal fibrosing alopecia, they carry significant risk of adverse events; two cases showed promising results using tofacitinib cream as a safer topical alternative.
3 citations
,
February 2000 in “Dermatologic Surgery” The document concludes that hair restoration has improved with follicular unit transplantation, making it more scientific and precise.
4 citations
,
August 2025 in “Bőrgyógyászati és Venerológiai Szemle” This study applied a novel method to the Italian economy and found that declining labor productivity from 1981-2004 was mostly due to a fall in total factor productivity growth.
3 citations
,
June 2005 in “Ophthalmology Clinics of North America” Follicular unit transplantation treats hair loss and restores eyebrows with short recovery and natural results.
43 citations
,
March 2009 in “Journal of Cellular and Molecular Medicine” This study suggests that TGF-β 2 plays a critical role in hair follicle morphogenesis and may enhance the effectiveness of future cell therapies for hair regrowth using expanded dermal papilla cells.
1 citations
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September 2023 in “eLife” This study found that TLR2 expression in hair follicle stem cells is crucial for hair follicle maintenance and regeneration, with TLR2-dependent activation potentially offering new therapeutic approaches for hair loss prevention through mechanisms involving immune pathways and CEP administration.
October 2012 in “한국미용학회지” This study reported that stress in early life negatively impacted hair growth in mice at older ages, while Tremella fuciformis Berk extracts partially protected against these effects.
13 citations
,
November 2021 in “Pediatric Dermatology” This study found that oral tofacitinib was effective and well tolerated for treating alopecia areata in most pediatric patients, with nearly 73% experiencing hair regrowth.
January 2025 in “Journal of Crohn s and Colitis” In this study, tofacitinib showed promising efficacy and safety for biologic-naïve elderly patients with moderate-to-severe ulcerative colitis, achieving steroid-free remission and clinical response over 52 weeks.
28 citations
,
January 2012 in “Case Reports in Medicine” This article discusses Hair-thread Tourniquet Syndrome in children, emphasizing the need for prompt examination and intervention to prevent severe complications, but reports no new clinical results.
5 citations
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May 2011 in “Movement Disorders” Finasteride significantly reduced tics and obsessive-compulsive symptoms in Tourette syndrome patients.