8 citations
,
August 2019 in “ACR Open Rheumatology” This review explores the biomechanical factors and signaling systems, like Wnt, involved in the pathophysiology of psoriatic nail lesions and reports no new results.
17 citations
,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” This report describes two young women with severe psoriasis and alopecia universalis, highlighting the possible but unstudied association between alopecia areata and metabolic syndrome.
1 citations
,
April 2016 in “Journal of The American Academy of Dermatology” Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.
This study reports the case of a 12-year-old girl who developed psoriatic alopecia after increasing her dose of the TNF-α inhibitor adalimumab for Crohn's disease, emphasizing psoriatic alopecia as a phenomenon associated with these medications.
This study found that patients with psoriasis have a significantly higher prevalence of autoimmune diseases and other physical and mental comorbidities compared to those without the condition.
17 citations
,
August 2019 in “Frontiers in Immunology” This review examines non-invasive methods for diagnosing inflammatory skin diseases like lupus erythematosus and psoriatic inflammation using samples from plucked hair and skin tape-strips, but no new clinical results are presented.
1 citations
,
October 2021 in “Cureus” This study found that platelet-rich plasma treatment led to significant reductions in lesion sizes for both plaque psoriasis and atopic dermatitis, with many patients achieving complete remission and no adverse events reported.
November 2024 in “Journal of Investigative Dermatology” Polygenic Score can help predict severe psoriasis and psoriatic arthritis.
April 2018 in “Journal of Investigative Dermatology” This study found that psoriasis patients value medication providing substantial clearance of symptoms at an average of $34,208/year, significantly below the annual cost of biologic treatments.
2 citations
,
April 2024 in “Dermatology Practical & Conceptual” This study emphasizes the importance of regular dental check-ups for patients undergoing systemic treatments for psoriatic disease, as it helps prevent oral complications associated with these medications. It recommends collaboration between dermatologists and oral health specialists to effectively manage and communicate these risks.
1 citations
,
July 2024 in “Journal of Investigative Dermatology” TAK-279 effectively reduces psoriasis symptoms and is safe.
April 2023 in “Journal of Investigative Dermatology” This study found that longer disease duration in psoriasis patients was significantly associated with increased incidence of cerebral atrophy, suggesting a potential need for central nervous system screening in these patients.
19 citations
,
November 2016 in “Dermatology and therapy” This study describes a case where stopping infliximab and using oral minocycline with topical treatments effectively resolved alopecia and scalp psoriasis in a woman with Crohn's disease.
9 citations
,
January 2015 in “Dermatology Online Journal” This case report describes a patient with Crohn's disease developing alopecia and psoriasiform skin lesions while on adalimumab treatment.
6 citations
,
January 1992 in “Journal of Dermatological Treatment” This review summarizes experimental studies on topical cyclosporin A for various skin conditions and reports no new clinical results; it also discusses the theoretical pharmacokinetics of topical application.
2 citations
,
November 2007 in “Clinics in dermatology” In this study, tofacitinib was found to be a promising treatment for adolescents with alopecia areata, showing significant hair regrowth in most patients with mild adverse effects, despite limitations like small sample size and lack of control group.
6 citations
,
January 2012 in “Journal of Biomedicine and Biotechnology” This report reviews peer-reviewed case studies indicating potential efficacy of ustekinumab for treating challenging forms of psoriasis but notes the need for further research on cost-effectiveness and risk-benefit.
7 citations
,
April 2013 in “International Journal of Rheumatic Diseases” This case report highlights a potential association between etanercept, a TNF-α blocker, and the onset of alopecia areata, suggesting complex interactions between anti-TNF-α treatments and hair follicle growth.
2 citations
,
May 2024 in “International Journal of Molecular Sciences” This study found that in a mouse model of psoriasis, depleting CD169+ macrophages led to milder symptoms and decreased inflammation, suggesting these macrophages play a crucial role in psoriasis development.
1 citations
,
August 2025 in “International Journal of Molecular Sciences” This narrative review suggests that nutraceutical insulin-sensitizing agents like myo-inositol, alpha-lipoic acid, and vitamins may improve glycemic control and reduce inflammation in insulin resistance-related skin disorders; however, more robust long-term trials are needed to confirm these findings and establish treatment regimens.
September 2023 in “Journal of the American Academy of Dermatology” This study suggests that using the International Psoriasis Council's classification, which includes body surface area, special areas, and treatment history, may identify more candidates for systemic therapy than by body surface area alone.
June 2025 in “Dermatopathology” This study reports that SARS-CoV-2 infection, COVID-19 vaccination, and off-label dupilumab treatment may exacerbate psoriasis, with overlapping inflammatory pathways involving cytokines like IL-17 and TNF-α. Histopathological similarities between psoriasis flares and COVID-19 skin manifestations were noted, suggesting a potential connection requiring further research.
7 citations
,
October 2022 in “Dermatology Practical & Conceptual” This study found that more than half of psoriasis patients used complementary and alternative medicine without informing their physicians, highlighting a need for increased awareness among dermatologists.
November 2022 in “Journal of Investigative Dermatology” This study provides evidence that ILC1-like cells can induce alopecia areata in previously healthy human hair follicles, challenging the view that it is solely an autoantigen-dependent autoimmune disease.
100 citations
,
August 2022 in “Microbial Cell Factories” This review discusses the interactions between skin microbiota and human skin health, examining how imbalances may contribute to skin diseases, and reports no new clinical results.
52 citations
,
February 2018 in “Diabetology & Metabolic Syndrome” This review discusses the association between various skin conditions and metabolic syndrome, reporting no new clinical results but suggesting a potential reciprocal relationship that warrants further investigation.
3 citations
,
March 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This review explores the advantages and limitations of using zebrafish models to study various skin diseases, but reports no new experimental results.
3 citations
,
August 2021 in “Cutis” This review examines CAM approaches for atopic dermatitis, psoriasis, and alopecia areata, providing dermatologists with current insights but includes no new clinical findings.
2 citations
,
July 2025 in “Scientific Reports” In this study, researchers found that dermatological diseases like atopic dermatitis, psoriasis, and hidradenitis suppurativa impact women's work performance and daily activities more severely than men's, with women reporting higher absenteeism and work impairment and lower work ability scores.
December 2024 in “Journal of Population Therapeutics and Clinical Pharmacology” According to this worldwide systematic review, psoriasis is a prevalent disease with adult prevalence ranging from 0.53% to 11.48%, more common in older populations and with substantial knowledge gaps in low and middle-income countries.