Psoriasis in the Limelight: The Remarkable Career of an Old Skin Disease

November 2007 in “ Clinics in dermatology ”

Michael P. Schön

psoriasis T-cells cytokines biologic therapies genetic factors immunological factors environmental factors

TLDR Tofacitinib may be an effective and safe treatment for adolescent alopecia areata.

The document discussed the significant advancements in understanding and treating psoriasis, a chronic skin disease, highlighting its complex pathogenesis involving genetic, immunological, and environmental factors. It emphasized the role of T-cells and cytokines in the disease's development and the impact of new biologic therapies targeting these pathways. The research was supported by the Rudolf Virchow Award and a European Union grant, reflecting the collaborative efforts to improve patient outcomes.

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community My Theory Regarding a Cause and Cure for Androgenetic Alopecia

in Treatment 98 upvotes 4 years ago

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

community Does finasteride/dutasteride reverse aging?

in Chat 45 upvotes 1 month ago

Finasteride and dutasteride can improve skin texture and reduce acne by lowering DHT but do not reverse aging. They may enhance skin and hair health for some, but can also cause side effects like dry skin and sexual dysfunction.

community Progress: From June 2022 (7 months of min + fin) to now (1 year) — I’ve lost so much density in this period and I have no idea why. I was getting pretty good resultup until that point. Is there anything else I can try? I’ve tried min, fin, tretinoin, micro needling, and castor oil. I feel hopeless.

in Progress Pictures 10 upvotes 1 year ago

The user lost hair density after 7 months of using minoxidil and finasteride and is seeking advice on other treatments after trying tretinoin, microneedling, and castor oil. Suggestions include checking for scalp conditions like eczema or psoriasis, changing minoxidil brands, and questioning hair dryer use and finasteride dosage.

community Please stop looking for a natural way to stop your hairloss

in Chat 247 upvotes 2 years ago

There is no natural way to stop hair loss; pharmaceuticals like minoxidil, finasteride, and RU58841 are the only effective treatments. Some users report success with minoxidil and microneedling, while others discuss the side effects of finasteride.

community What’s the most effective way to beat Serb Derm?

in Treatment 7 upvotes 2 months ago

OP struggles with scalp flakes causing hair loss and has tried Selsun Blue, Ketoconazole, and ZPT Shampoo without success. Suggestions include using salicylic acid shampoo, shaving the head, using Nizoral, and combining treatments like Minoxidil and finasteride.

community 18 month since starting treatment. Minoxidil 5% twice a day and Finasteride 1 mg everyday.

in Progress Pictures 735 upvotes 8 months ago

The conversation is about an 18-month hair loss treatment with Minoxidil 5% used twice daily and Finasteride 1 mg taken every day, showing significant progress. Participants discuss the form of Minoxidil used, side effects like dandruff, the time taken to see results, and encouragement from the visible improvement.

Related Research

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research Successful Treatment of Severe Alopecia Areata With Oral or Topical Tofacitinib

4 citations, July 2018 in “PubMed”

Oral and topical tofacitinib can help regrow hair in people with severe alopecia areata.