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GlossaryImmunological Factors

components of the immune system that defend against threats

Immunological factors, also known as immune factors, refer to components of the immune system that play a role in defending the body against infections, diseases, and foreign substances. These include various cells (like T-cells and B-cells), antibodies, cytokines, and other molecules that identify and neutralize harmful agents. In the context of hair and alopecia, immunological factors can influence conditions like alopecia areata, where the immune system mistakenly attacks hair follicles, leading to hair loss.

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research Global Burden of Alopecia Areata and Associated Diseases: A Trend Analysis From 1990 to 2021

February 2025 in “PubMed”

Alopecia areata cases have increased globally, affecting mostly women aged 30-34, with links to other health issues.

research Capillary Impacts of Covid-19: The Link Between Acute Telogen Effluvium and Alopecia Areata - An Integrative Review

February 2024 in “Recima21”

Covid-19 can cause hair loss due to immune and psychological factors.

research Fibrosing Frontal Alopecia: A Comprehensive Study to Understand Its Etiology

May 2024 in “International Seven Journal of Multidisciplinary”

More research is needed to better understand and treat Fibrosing Frontal Alopecia.

research From Targets to Treatments: Bridging Autoimmune Research to Advance Understanding of Alopecia Areata

November 2015 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings”

Alopecia areata is now understood to be driven by genetic and immune factors.

research Psoriasis in the Limelight: The Remarkable Career of an Old Skin Disease

2 citations , November 2007 in “Clinics in dermatology”

Tofacitinib may be an effective and safe treatment for adolescent alopecia areata.

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community Making your own RT1640 in China

in Research/Science 4 years ago

RT1640, a combination of cyclosporin A, minoxidil, and RT175, is discussed as a potential treatment for hair regrowth and repigmentation. The unique formulation aims to enhance hair follicle growth and restore hair pigment without the negative side effects of immunosuppressants.

community How I recovered from 4+ years of severe balding ages 20-24 by dieting, lifestyle changes and ONLY using topical minoxidil

in Progress Pictures 473 upvotes 7 months ago

A user reversed severe hair loss with dieting, lifestyle changes, and topical minoxidil, highlighting reduced inflammation and body fat. The conversation debates finasteride's effectiveness and the impact of diet and lifestyle on hair health.

community 18 months Dut - Shed after shed without any gains

in Update 115 upvotes 8 months ago

Dutasteride caused persistent hair shedding and no improvement for 18 months, leading to a switch back to finasteride. The user also uses oral minoxidil and plans to focus on better scalp health.

community My hair stopped falling out after I quit smoking

in Update 60 upvotes 1 year ago

Quitting smoking led to reduced hair loss for the original poster, who also used finasteride and topical minoxidil. Other users shared mixed experiences with smoking and hair loss, with some noticing improvements after quitting and others seeing no change.

community 8 years of hair loss, turning 30 next month

in Progress Pictures 148 upvotes 8 months ago

The user has been dealing with hair loss for 10 years, worsened by psoriasis, and uses minoxidil and finasteride. They seek advice on managing psoriasis and hair loss, with suggestions to see a dermatologist, try different shampoos, and be patient.