Prevalence of Autoimmune Diseases and Other Comorbidities in Patients With Psoriasis in the United States
April 2012
psoriasis psoriatic arthritis rheumatoid arthritis ankylosing spondylitis ulcerative colitis Crohn's disease autoimmune diseases Charlson comorbidity index hypertension chronic pulmonary diseases diabetes hypothyroidism deficiency anemias valvular diseases solid tumor without metastases psychoses peripheral vascular disease Pso RA UC CD CCI
TLDR People with psoriasis have more health problems, including autoimmune diseases, than those without it.
The study titled "Prevalence of autoimmune diseases and other comorbidities in patients with psoriasis in the United States" found that patients with psoriasis (Pso) have a significantly higher comorbidity burden compared to Pso-free patients, including a higher prevalence of autoimmune diseases and other physical and mental comorbidities. The study involved 106,128 matched pairs of Pso and Pso-free patients, with a mean age of 52 years and 52% female. It was observed that 77% of Pso patients had mild Pso and 23% had moderate-to-severe Pso. Pso patients had a higher mean Charlson comorbidity index (CCI) score (1.06 vs 0.74) and a significantly higher prevalence of autoimmune diseases such as psoriatic arthritis (10.2%), rheumatoid arthritis (8.1%), ankylosing spondylitis (1.5%), ulcerative colitis (1.0%), and Crohn's disease (0.8%), as well as other comorbidities like hypertension, chronic pulmonary diseases, diabetes, hypothyroidism, deficiency anemias, valvular diseases, solid tumor without metastases, psychoses, and peripheral vascular disease. The study was funded by Celgene Corporation.
