research Abstracts
This review discusses autoimmune blistering diseases across species and highlights new treatment efficacy findings and ongoing trials, but it reports no new clinical results.
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30 / 755 resultsresearch AVALIAÇÃO DO USO DE TELAS DIGITAIS POR CRIANÇAS E ADOLESCENTES EM TEMPOS DE PANDEMIA
Children's screen time increased during the pandemic, causing various health issues.
research Cutaneous manifestations of systemic infection in children
This review discusses diagnostic approaches for childhood skin diseases with fever through clinical observations and covers recent advances in understanding the pathogenesis and epidemiology of related infections, without reporting new clinical results.
research World Dermatologic Literature
Prednisone has risks for lupus patients, isotretinoin is safe for mental health, transplant patients risk skin cancer, and various treatments are effective for specific skin conditions.
research Yale–New Haven Hospital top contender in Abbott quality awards
This article discusses Yale–New Haven Hospital's high ranking as a contender in the Abbott quality awards and reports no new research findings.
research Immunization and Bacterial Pathogens in the Oropharynx as Risk Factors for Alopecia Areata
This study found that a history of immunization and throat carriage of bacterial pathogens, including Streptococcus pyogenes, were associated with increased risk of developing alopecia areata.
research Immunoglobulin E and Serum Interleukin-13 and Bacteria in Patients with Alopecia Areata
This study found that patients with alopecia areata had increased levels of serum immunoglobulin E and interleukin-13 compared to healthy controls, with additional variation in levels observed across age and weight.
research Expanding the Nude SCID/CID Phenotype Associated with FOXN1 Homozygous, Compound Heterozygous, or Heterozygous Mutations
This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.
research Treatment of invasive aspergillosis with itraconazole
This study suggests that itraconazole may significantly improve therapy for aspergillosis, with 12 out of 15 evaluable patients responding to the treatment.
research Management of congenital ichthyoses: European guidelines of care, part two
These guidelines review the management of complications and specific forms of congenital ichthyosis and report no new results; they summarize expert and evidence-based recommendations for clinicians.
research Skin signs of systemic diseases
This review discusses skin signs that can indicate systemic diseases and provides no new clinical results; it aims to aid physicians in diagnosing these conditions.
research Recent advances in drug repositioning and rediscovery for different therapeutic activities utilizing updated technological approaches
This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.
research Botanicals With Dermatologic Properties Derived From First Nations Healing: Part 1—Trees
This study assessed the dermatologic potential of western red cedar, white spruce, birch, balsam poplar, and black spruce used in First Nations medicine, highlighting several active compounds relevant to dermatology, but noted a lack of high-quality evidence in existing research.
research Performance of Chlorhexidine and Ophytrium-Containing Shampoo and Mousse in Dogs with Cutaneous Yeast Imbalance
In this study on dogs with yeast imbalances and dermatological signs, a protocol using chlorhexidine and Ophytrium products significantly reduced Malassezia pachydermatis counts and improved pruritus and irritation scores over 21 days, earning positive assessments from veterinarians and owners in most cases.
research IMMUNOLOGICAL AND SOME BIOLOGICAL BIOMARKERS INVESTIGATION IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS
This study found that all examined biomarkers and clinical features were elevated in systemic lupus erythematosus patients, particularly ANA and Anti-dsDNA autoantibodies, but no single biomarker was sensitive or specific enough for diagnosis.
research Skin Disorders in Athletes: Professional and Recreational Sports
This study discusses how dermatological issues in athletes can arise from or be exacerbated by mechanical trauma, infections, and environmental factors, highlighting the importance of thorough history and examination to differentiate these from other skin conditions.
research American Academy of Veterinary Dermatology and American College of Veterinary Dermatology Annual Meeting, Norfolk, Virginia 4-8 April 2001
This article reviews topics from the American Academy of Veterinary Dermatology and American College of Veterinary Dermatology Annual Meeting and contains no new clinical findings.
research The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic
This review discusses ciprofloxacin resistance mechanisms in bacteria and explores new approaches, such as combining it with other antibacterial agents, to enhance its effectiveness against resistant infections.
research Progress in Pluronic F127 Derivatives for Application in Wound Healing and Repair
This review discusses the potential of Pluronic F127-derived hydrogels for wound healing, examining their applications in various wound types and exploring underlying mechanisms and their interaction within the wound microenvironment.
research Opportunities and challenges of bacterial extracellular vesicles in regenerative medicine
This review discusses the potential of bacterial extracellular vesicles in regenerative medicine, highlighting their advantages in addressing current EV challenges, and provides strategies for optimizing their preparation; it reports no new clinical results.
research Comprehensive Review of Perilla frutescens: Chemical Composition, Pharmacological Mechanisms, and Industrial Applications in Food and Health Products
This study highlights the diverse applications of *Perilla frutescens* in traditional medicine, cuisine, and industrial settings, noting its significant antioxidant and antimicrobial properties in experimental models, as well as research efforts to enhance its bioactive content and ensure safety and standardization.
research Follicular contact dermatitis revisited: A review emphasizing neomycin-associated follicular contact dermatitis
This review discusses the clinical and pathologic features of follicular contact dermatitis, highlighting neomycin as a potential cause, and reports no new clinical results.
research Hydrogels Modulating the Microbiome: Therapies for Tissue Regeneration with Infection Control
This review discusses how functionalized hydrogels can modulate the microbiome to aid tissue regeneration and infection control, highlighting their potential to deliver therapeutic agents effectively and support beneficial immune responses.
research Cathelicidins: Opportunities and Challenges in Skin Therapeutics and Clinical Translation
This review discusses the potential of cathelicidins in treating skin conditions but highlights significant challenges, including unclear clinical efficacy, safety concerns, and bacterial resistance, that must be addressed for successful medical application.
research TONGUE, RED
This abstract compiles a list of medical syndromes and conditions related to tongue abnormalities and other systemic features but reports no new research findings.
research Androgen Receptor Blockade Induces the Phagocytosis of MRSA and Pseudomonas aeruginosa by Monocyte-Derived Macrophages In Vitro
This study found that in vitro environments simulating testosterone levels in elderly males, testosterone and its metabolite DHT significantly reduced macrophages' ability to phagocytize MRSA and Pseudomonas aeruginosa, suggesting AR manipulation and inhibiting testosterone-DHT conversion might help fight wound infections in the elderly.
research Androgen Receptor Blockade Induces the Phagocytosis of MRSA and Pseudomonas aeruginosa by Monocyte-Derived Macrophages In Vitro
This study found that testosterone and its metabolite DHT reduced macrophage-mediated phagocytosis of bacteria like MRSA and P. aeruginosa in vitro, and blocking testosterone's conversion to DHT improved bacterial clearance, suggesting potential therapeutic strategies for combating wound infections in the elderly.
research Repurposing Finasteride as a quorum sensing inhibitor in Pseudomonas aeruginosa
In laboratory settings, this study found that finasteride repurposed as a quorum sensing inhibitor significantly reduced virulence factors of Pseudomonas aeruginosa, including biofilm formation by 45% and pyocyanin production by 49%, suggesting potential for treating infections.
research The Human Innate Immune Protein Calprotectin Elicits a Multimetal Starvation Response in Pseudomonas aeruginosa
This study found that multimetal starvation by the immune protein calprotectin triggers unique regulatory responses in Pseudomonas aeruginosa, beyond those seen with individual metal shortages.
research Therapeutic targeting of ocular diseases with emphasis on PI3K/Akt, and OPRL pathways by Hedera helix L. saponins: a new approach for the treatment of Pseudomonas aeruginosa-induced bacterial keratitis
In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.