Recent Advances in Drug Repositioning and Rediscovery for Different Therapeutic Activities Utilizing Updated Technological Approaches

    July 2025 in “ Molecular Diversity ”
    Eman S. Nossier, Manal M. Anwar, Mohamed Ayman El‐Zahabi
    Studysummary This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.
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    Research cited in this study 10

    1. Advances in Topical Therapies for Clinically Relevant and Prevalent Forms of Alopecia Life · 2024
    2. Drug Repurposing: Clinical Practices and Regulatory Pathways Perspectives in Clinical Research · 2024
    3. How Drug Repurposing Can Advance Drug Discovery: Challenges And Opportunities Frontiers in Drug Discovery · 2024
    4. Repurposing Existing Drugs for the Treatment of COVID-19/SARS-CoV-2: A Review of Pharmacological Effects and Mechanism of Action Heliyon · 2024
    5. Hair Regrowth Boosting Via Minoxidil Cubosomes: Formulation Development, In Vivo Hair Regrowth Evaluation, Histopathological Examination, and Confocal Laser Microscopy Imaging International Journal of Pharmaceutics · 2023
    6. Are Sex Hormones Promising Candidates to Explain Sex Disparities in the COVID-19 Pandemic? Reviews in endocrine and metabolic disorders · 2021
    7. Review of Oral Minoxidil as Treatment of Hair Disorders: In Search of the Perfect Dose 2021
    8. Drug Repurposing: Hypothesis, Molecular Aspects, and Therapeutic Applications IntechOpen eBooks · 2020
    9. Drug Repositioning: Current Approaches and Their Implications in the Precision Medicine Era Expert review of precision medicine and drug development · 2018
    10. DrugNet: Network-Based Drug–Disease Prioritization by Integrating Heterogeneous Data Artificial Intelligence in Medicine · 2015