July 2026 in “Stem Cell Research & Therapy” This commentary suggests that shifting from inconsistent autologous PRP to more standardized PRP-inspired formulations could improve treatment consistency for alopecia, emphasizing the need for careful characterization and clinical studies to validate safety and efficacy.
14 citations
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October 2020 in “Natural Products and Bioprospecting” This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.
6 citations
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August 2025 in “Frontiers in Bioengineering and Biotechnology” This review discusses the evolution of platelet concentrates in regenerative medicine, highlighting a proposed function-driven classification that distinguishes three generations of PCs by biological activity rather than development order, with third-generation exosome-based therapies showing superior therapeutic efficacy over earlier formulations.
September 2025 in “Dermatology and Therapy” This systematic review and meta-analysis found that platelet-rich plasma (PRP) therapy is effective in increasing hair density and reducing hair loss for alopecia, with variations in response based on activation status.
August 2026 in “Frontiers in Veterinary Science” This review article analyzes the differences and challenges in managing nonscarring alopecia across humans and companion animals like dogs and cats, highlighting the importance of species-specific clinical trials and treatment formulations due to differences in hair and skin characteristics.
July 2025 in “Cosmoderma” This review discusses the various applications of platelet-rich plasma in dermatology, particularly its potential in esthetic dermatology and hair and scalp conditions, but reports no new clinical findings.
January 2026 in “Digital Repository (National Repository of Grey Literature)” In this study, two formulations of platelet-rich plasma and two mesotherapy products showed varying degrees of effectiveness in improving hair thickness, density, and count in androgenetic alopecia patients after six months, with MZT1 and PRP2 achieving statistically significant improvements in most measures.
August 2025 in “The American Journal of Medical Sciences and Pharmaceutical Research” This study suggests that noninvasive carboxytherapy methods, like gel formulations and device-assisted delivery, can significantly improve skin conditions with high safety and no recovery time, particularly in sensitive areas.
March 2017 in “Open access journal of surgery” This review discusses the historical development of platelet-rich fibrin from fibrin glue to platelet-enriched formulations and reports no new clinical results.
June 2024 in “Skin Appendage Disorders” In this study, injections of PRP and MZT products significantly improved hair thickness, density, and count in AGA patients over six months, with variability observed in the extent of improvement between different formulations.
14 citations
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April 2020 in “Journal of Cosmetic Dermatology” In this study, intradermal injections of QR678 were found to significantly reduce hair fall in men with androgenetic alopecia over 6 months, with superior improvements in hair density and thickness compared to PRP.
June 2026 in “Journal of Comprehensive Dermatology” This study reviewed the evidence on minoxidil's effectiveness for androgenetic alopecia, finding that 5% topical minoxidil is the most effective monotherapy for men, while 2% is similarly effective for women. Genetic markers can predict response, and new formulations like foam and gel improve tolerability.
1 citations
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August 2023 in “Bioengineering” This review explores the potential benefits of platelet-rich plasma for anti-aging and tissue regeneration, especially in orthopedic applications like osteoarthritis, but it reports no new clinical results.
3 citations
,
March 2023 in “National Journal of Health Sciences” This article reviews the potential of platelet-rich plasma therapy in managing diabetic foot ulcers but reports no new clinical findings, highlighting the need for further controlled trials to evaluate its effectiveness.
2 citations
,
November 2023 in “Journal of Cosmetic Dermatology” This review examines the bibliometric landscape of research on platelet-rich plasma in cosmetic therapy from 2001 to 2022 and reports no new clinical findings, but highlights research trends and future directions.
April 2025 in “Diagnostics” This review synthesizes data suggesting that managing inflammation and oxidative stress may enhance the effectiveness of PRP therapy for hair regeneration, though standardizing PRP protocols remains challenging.
9 citations
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July 2019 in “Journal of cosmetic dermatology” This pilot study suggests that topical PRP may improve facial rejuvenation, with observed enhancements in collagen production and skin architecture over 8 weeks.
2 citations
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January 2023 in “Eastern Journal Of Medicine” This review discusses the use, efficiency, and preparation methods of autologous platelet concentrates in wound healing and periodontal regeneration, but it reports no new clinical findings.
July 2025 in “JOJ Dermatology & Cosmetics” This study observed that both polynucleotides (PN HPT™) and platelet-rich plasma (PRP) improved hair density and quality in men with androgenetic alopecia, with comparable outcomes and no significant adverse events.
February 2024 in “Actas Dermo-Sifiliográficas” This study involved a Delphi-method consensus from 34 Spanish dermatologists, outlining structured recommendations for managing androgenetic alopecia based on available scientific evidence and expert opinions, aiming to guide clinical practice amid limited treatment approvals and varying effectiveness.
February 2026 in “Frontiers in Bioengineering and Biotechnology” This review discusses the current evidence on platelet-rich plasma therapy's biological mechanisms and clinical applications, highlighting its promise in regenerative medicine and the challenges to its integration in nursing practice.
12 citations
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April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
August 2010 in “The Journal of Dermatology” The document concludes that low-dose acne treatment is most suitable for moderate acne, with high patient satisfaction and low relapse rates.
15 citations
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April 2025 in “Journal of Clinical Medicine” This review reports that platelet-rich plasma may be more effective for musculoskeletal conditions when prepared with high platelet doses and low leukocyte content, but further trials are needed to confirm optimal formulations.
9 citations
,
June 2025 in “Journal of Clinical Medicine” The authors concluded that while PRP is a promising and well-tolerated treatment for early to moderate knee osteoarthritis, standardizing preparation protocols, patient selection, and outcome reporting is crucial to enhance comparability and inform clinical practice.
This study found that a single dose of PRP with 100 billion platelets significantly reduced pain and improved knee function in patients with osteoarthritis, but did not alter joint structure on MRI.
6 citations
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January 2025 in “World Journal of Orthopedics” This review discusses the use of platelet rich plasma in ACL reconstruction, indicating potential benefits in early healing and complication reduction, but notes inconsistent long-term outcomes and a need for more research.
January 2026 in “Journal of Cosmetics Dermatological Sciences and Applications” This review reports that while platelet-rich plasma shows promise as a safe treatment for various types of hair loss, variability in studies limits definitive conclusions on its effectiveness.
January 2024 in “International Journal of Scientific Research in Science and Technology” This review analyzes Platelet-Rich Plasma therapy for facial aesthetics, discussing its principles, efficacy, safety, and future research directions, but reports no new clinical results.
August 2023 in “International journal of medical science and clinical research studies” This review discusses platelet-rich plasma (PRP) therapy for pediatric surgical wound care, evaluating its potential as an adjunctive treatment, but reports no new clinical results.