The Evolution of Platelet-Rich Plasma: A 70-Year-Old History

July 2025 in “ Cosmoderma ”

Lidiya Todorova

platelet-rich plasma PRP growth factor concentrate GFC exosome-rich formulations alopecia regenerative dermatology esthetic dermatology tissue regeneration wound healing scar revision skin rejuvenation

TLDR PRP therapy has evolved over 70 years and is used for healing and cosmetic purposes, but its effectiveness varies.

Platelet-rich plasma (PRP) therapy, with a 70-year history, began in transfusion medicine and has expanded into fields like regenerative and esthetic dermatology, particularly for hair and scalp conditions. It is used for tissue regeneration, wound healing, scar revision, skin rejuvenation, and alopecia. Recent advancements include growth factor concentrate (GFC) and exosome-rich formulations to enhance regenerative potential. However, evidence of PRP's efficacy varies across applications, with some areas showing more promising results than others.

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