2 citations
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September 1996 in “Journal of Applied Polymer Science” This study found that treating hair with aqueous KCN converts disulfide bonds to monosulfide crosslinks, affecting the elasticity and crosslink distribution in hair microstructures.
August 2025 in “Applied Sciences” This study found that peroxide-rich plasma-activated water caused minimal morphological damage to hair, while nitrate-rich plasma-activated water induced significant damage, especially in porous hair types.
37 citations
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August 2014 in “Journal of experimental botany” This study identified the AtPRPL1 gene in Arabidopsis thaliana as being involved in cell elongation processes, despite unclear changes in cell wall composition from its altered expression.
27 citations
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April 2018 in “Artificial Cells Nanomedicine and Biotechnology” This study reported that recombinant human hair keratins, K37 and K81, showed higher purity and enhanced fibrin clot formation compared to traditional extracts, reducing bleeding time and blood loss in rat injury models.
4 citations
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January 2015 in “Sen'i Gakkaishi” This study proposed a network model for the cross-linked structure of keratin-associated proteins in hair and wool fibers, suggesting notable differences between the two, potentially affecting hair fiber elasticity.
1 citations
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January 2013 in “PubMed” In this study, treating hair with thioglycolic acid was found to alter disulfide bond patterns in keratin-associated proteins, shifting them from an ellipsoidal to a near-spherical shape.
1 citations
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April 2023 in “Langmuir” This study used molecular dynamics simulations to model the outer surface of human hair, illustrating complex behavior and potential adsorption interactions with fatty acids, which may inform cosmetic formulation development.
June 1967 in “Journal of Cellular Physiology” This study developed an in vitro 3D organoid model using dermal papilla spheroids and found that it enhances growth factor expression and extracellular matrix production, which could aid drug screening for hair regeneration.
2 citations
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October 2022 in “Journal of structural biology” This study found that age-related hair thinning in Caucasian women over 50 involves significant structural changes within the hair follicle, suggesting an "aged hair program" rather than just producing thinner hairs.
This study found that modern styling cosmetics can significantly alter hair structure through changes in interfacial chemistry and cohesion, particularly when applied to already damaged hair.
January 2026 in “Biomaterials and Biosystems” This study extracted water-soluble keratin particles from chicken feathers and verified their structural properties, observing no irritative potential on hen's eggs and positive physiological effects on human skin cells, suggesting their suitability for use on damaged or irritated skin.
May 2026 in “International Journal of Cosmetic Science” This study found that repeated exposure to ozonated water caused oxidative changes in hair proteins, lipids, and pigments, leading to altered hair properties, with minimal effects on shine and color.
September 2018 in “Digital Access to Scholarship at Harvard (DASH) (Harvard University)” In this study, FN-based fiber scaffolds designed using Rotary Jet-Spinning were shown to enhance wound healing and reduce scar formation in a mouse model, suggesting potential for regenerating healthy skin structure.
4 citations
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August 2011 in “Journal of Food Biochemistry” This study reports that α-casein in bovine milk can form stable complexes with zinc, potentially useful for fortifying milk-based products to enhance zinc availability.
In this study, researchers developed vegan exosome-like vesicles from microalgae that mimic mammalian exosomes, demonstrating promising in vitro, ex vivo, and clinical effects such as improved wrinkle depth and elasticity, making them a potential alternative in cosmetic applications.
3 citations
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January 2016 In this study, NuMA's microtubule-binding domain was found to be crucial for correct spindle orientation and skin differentiation, with its loss leading to neonatal lethality in mice.
March 2010 in “International Journal of Cosmetic Science” This study found that oxidative treatment with peracetic acid dissociates some disulfide bonds in human hair fibers while maintaining the crystalline structure, suggesting different mechanisms stabilize different regions of intermediate filaments.
8 citations
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January 2023 in “International journal of molecular sciences” This study reveals that transglutaminase activity is widespread in integumentary structures of mammals and birds, suggesting it plays a significant role in the cornification of hard skin appendages like nails and feathers.
1 citations
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March 2025 in “Frontiers in Physiology” This study identified key genes linked to immune cells and potential therapeutic compounds for alopecia areata by evaluating upregulated genes from patient datasets, highlighting T and NK cell involvement in hair follicle attack and suggesting drug candidates through molecular docking and dynamics simulations.
May 2026 in “Research Square” This research reports that the polyG fragment within the Hoxc13 protein alters its gene regulatory functions, which could have influenced mammalian hair evolution by affecting pathways related to hair follicle development.
86 citations
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May 2002 in “Journal of Investigative Dermatology” This study characterized a new human keratin, hK6irs1, specifically found in the inner root sheath of hair follicles, which suggests its role in the structural integrity and guidance of growing hair shafts.
9 citations
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January 1989 in “Sen'i Gakkaishi” This study found that moisture sorption properties of wool and hair fibers from various animals were similar, despite different structural features, with sorbed water being more ordered than liquid water.
2 citations
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December 2023 in “Royal Society of Chemistry eBooks” The book discussed in this abstract is a comprehensive guide to hair analysis, detailing the latest methods and applications across various fields such as toxicology and drug monitoring, designed for both newcomers and experts in the field.
2 citations
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January 2000 in “Elsevier eBooks” The document explains how hair is studied in forensics to identify its source and its role in criminal investigations.
1 citations
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January 2009 in “Elsevier eBooks” This review discusses the mechanisms by which laser treatment affects hair structures and growth, highlighting its potential for permanent hair reduction and associated skin damage, but reports no new experimental results.
January 2026 in “Preprints.org” In this study, researchers identified four novel variants in the FGF5 gene associated with the long-haired phenotype in dogs, suggesting additional unexplored genetic factors contribute to this trait beyond the known Lh1-Lh5 alleles.
This review discusses the role of nutrients in hair graying management and finds a possible link between low copper, iron, and vitamin B12 levels and premature hair graying.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that certain tandem repeats predict darker hair color across diverse ancestry groups and can contribute to a polygenic score for hair color, independent of SNP variation.
This study suggests that specific genetic changes, including mutations in protein-coding genes and noncoding regions, have contributed to the evolution of hairlessness in multiple mammalian species.
June 2017 in “University of the Arts London Research Online (University of the Arts London)” This study compared the effects of three compounds on structural and sensory benefits for bleached hair when applied with or after bleaching, observing that their application may mitigate bleaching-induced damage.