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New treatments for male hypogonadism are effective and should be personalized.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Minoxidil and finasteride treat hair loss; more research needed for other options.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Stress can worsen skin conditions by affecting hormone levels and immune response.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.

Inactive hair follicle stem cells help prevent skin cancer.

Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.

Certain bacteria and fungi are linked to healthy scalps and dandruff, suggesting that the scalp's microbial balance affects its health.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Some systemic treatments work for nail psoriasis but can have serious side effects.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Neurosteroids show promise for treating epilepsy and more research is needed.

The triterpenoids from Ganoderma lucidum can block testosterone effects and may help treat enlarged prostate.

PEGL-DOX causes Hand-Foot Syndrome due to skin reactions from prolonged circulation and ROS generation.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Fat from the body can help improve hair growth and scars when used in skin treatments.

Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.

RANK-RANKL signaling is essential for hair growth and skin health.