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Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

Keratin protein production in cells is controlled by a complex system that changes with cell type, health, and conditions like injury or cancer.

FP-1 is a key protein in rat hair growth, active only during the growth phase.

Understanding intermediate filaments helps explain hair health and related diseases.

A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.

WWP2 is crucial for tooth development in mice.

The technique showed that human hair has two main parts, with 68% being rigid and the rest flexible, and water swelling affects its structure.

Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.

The research found that a protein called caveolin-1 is reduced in psoriasis, but reintroducing it can help alleviate some psoriasis symptoms.

A second domain of high sulfur KAP genes on chromosome 21q23 is crucial for hair structure.

BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

A specific gene mutation causes congenital hair loss.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

The document concludes that the androgen receptor's structure and function are complex, affecting how it regulates genes and is involved in diseases like prostate cancer.

The Notch signaling pathway helps in mouse hair development through a noncanonical mechanism that does not rely on RBPj or transcription.

Mutations in hKAP1 genes may cause hereditary hair disorders.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

A new gene variant in the DSP gene is linked to a unique type of hair loss.

Testosterone increases heart and blood pressure issues in rats with endotoxemia, and stopping testosterone production can reduce these problems.

Deleting part of a gene in mice causes wavy hair and high pup loss.

CTCF protein is essential for skin and hair follicle development in mice.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Scientists successfully made a human growth factor in a plant, which could help with hair growth and bone development.

Foxn1 is important for fat development, metabolism, and wound healing in skin.

Activin A speeds up ear hair cell differentiation, while Follistatin slows it down.

Claudin expression changes help the skin respond to injury.

High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.