research A New Look at the 5-Alpha-Reductase Inhibitor Finasteride
Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.
Search
forProducts matching "prostatic tissue"
Tracking 1 products like 132 URODART 0.5MG 28 capsule from by companies like Minoxidil Express. View product »
Sort by
Research
60-90 / 1000+ results 
research PNU 157706, A Novel Dual Type I and II 5α-Reductase Inhibitor
PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.
research Finasteride: The First 5α-Reductase Inhibitor
Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.
![Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions](/images/research/2aedba8c-b0ac-4fa3-9ac7-9f375a016bba/small/15581.jpg)
research Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions
Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
research Clinical Use of 5α-Reductase Inhibitors
Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.
research Serum Prostate Specific Antigen Levels in Women with Androgenetic Alopecia
Women with androgenetic alopecia (hair loss) have normal prostate specific antigen levels but higher testosterone levels.
research Finasteride
Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
research Sex Steroid Synthesis in Human Skin In Situ: The Roles of Aromatase and Steroidogenic Acute Regulatory Protein in the Homeostasis of Human Skin
Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
research The Clinical Development of a 5α-Reductase Inhibitor, Finasteride
Finasteride effectively treats BPH, but needs more trials to understand potential.
research Validated HPTLC Method for the Simultaneous Determination of Alfuzosin, Terazosin, Prazosin, Doxazosin, and Finasteride in Pharmaceutical Formulations
Method can accurately measure five BPH drugs at once.
research A Retrospective Study of Clinical Outcomes of Alpha-Blocker or Finasteride Monotherapy Followed by Combination Therapy: Determination of the Period of Combination Therapy of Alpha-Blocker and Finasteride
Combination therapy for 9+ months maintains symptom improvements after stopping alpha-blockers or finasteride.
research Is Dehydroepiandrosterone a Hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Rat Steroid 5α-Reductase Kinetic Characteristics: Extreme pH-Dependency of the Type II Isozyme in Prostate and Epididymis Homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Six Weeks Finasteride Monotherapy Before TURP: Does It Improve Quality of Life in Early Postoperative Period?
Finasteride before TURP reduces blood loss and slightly improves early postoperative quality of life.
research Finasteride Inhibits 5α-Reductase Activity in Human Dermal Fibroblasts: Prediction of Its Therapeutic Application in Androgen-Related Skin Diseases
Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.
research The 5 Alpha-Reductase Isozyme Family: A Review of Basic Biology and Their Role in Human Diseases
The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function
A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
research Peripheral Androgens And The Role Of Androstanediol Glucuronide
Androstanediol glucuronide is a reliable marker for hirsutism in women.
research Preponderance of Serum and Intra-Hepatic 5α-Dihydrotestosterone in Males with Hepatocellular Carcinoma Despite Low Circulating Androgen Levels
Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.
research Design, Synthesis, and Biological Evaluation of Novel Androst-3,5-Diene-3-Carboxylic Acid Derivatives as Inhibitors of 5α-Reductase Type 1 and 2
New chemical compounds were made that effectively block an enzyme linked to prostate growth.
research What Do We Know About 5-Alpha Reductase Inhibitors?
Finasteride and dutasteride are effective for male hair loss and enlarged prostate but may cause reversible sexual side effects.
research Diseases Of The Canine Prostate Gland
The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.
research Dihydrotestosterone and 5α-Reductase: Role in Hair Loss and Prostate Health
Dihydrotestosterone and 5α-Reductase play a role in hair loss and prostate health, and finasteride can increase hair growth in men without affecting sperm production, but it doesn't work for postmenopausal women with hair loss.
research Treatment of Hirsutism with 5α-Reductase Inhibitors
New compounds may soon be tested to treat excessive hair growth in women.
research Finasteride: A Slow-Binding 5-Alpha-Reductase Inhibitor
Finasteride slowly binds to 5-alpha-reductase, affecting enzyme stability and inhibitor potency.
research Impact of Cernitin on Induced Chronic Prostatitis in Animal Model for Understanding Management of Lower Urinary Tract Symptoms
Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research Key Targets of Hormonal Treatment of Prostate Cancer: The Androgen Receptor and 5α-Reductase
Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.
research Kinetic Analysis of LY320236: Competitive Inhibitor of Type I and Non-Competitive Inhibitor of Type II Human Steroid 5α-Reductase
LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
research Hot Flashes in a Young Girl: A Wake-Up Call Concerning Serenoa Repens Use in Children
Serenoa repens (saw palmetto) may cause side effects like hot flashes in children and needs more research for safety in pediatric use.