Impact of Cernitin on Induced Chronic Prostatitis in Animal Model for Understanding Management of Lower Urinary Tract Symptoms
November 2021
in “
Phytomedicine plus
”
TLDR Cernitin™, a pollen extract, was found to significantly reduce pain and inflammation in rats with chronic prostatitis, suggesting it could be a useful alternative to certain anti-inflammatory drugs.
The study examined the effects of Cernitin™, a pollen extract, on chronic prostatitis in male Sprague Dawley rats. The results indicated that Cernitin™ significantly reduced pain and inflammation, as evidenced by decreased levels of inflammatory markers COX-2 and MCP-1. Additionally, Cernitin™ treatment led to a significant reduction in prostate weight and decreased expression of Ki-67, androgen receptor, and 5α-reductase proteins, which are associated with cell proliferation and testosterone conversion. Despite the study's limitations, such as a short treatment period and a small number of animals, the findings suggest that Cernitin™ could be a valuable alternative to nonsteroidal anti-inflammatory drugs in managing chronic prostatitis and chronic pelvic pain syndrome.
