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The document concludes that understanding health requires considering evolutionary perspectives on reproductive fitness, and recognizing the complexity of factors like diet, testosterone, and sexual orientation.

Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Finasteride before TURP reduces blood loss and slightly improves early postoperative quality of life.

Finasteride helps reduce heart issues and improves heart function.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Injecting platelet-rich plasma into the scalp stimulates hair growth, increases hair density, and treats hair loss effectively with minimal side effects.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Finasteride helps protect brain in old male rats.

Adding stem cells to fat grafts for facial rejuvenation might improve outcomes, but more research is needed to confirm safety and effectiveness.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

The pumpkin seed oil niosomes are promising for skin and hair treatments because they are stable and effectively deliver the oil.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.

Eating a lot of soy might lower the chance of early hair loss in men likely to get it.

Platelet-rich plasma (PRP) injections effectively treat hair loss and thinning in both men and women, with high satisfaction and no major side effects.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride reduces hair growth better, but spironolactone has more side effects.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Finasteride may help treat chronic CSC, improving vision.

The enzyme 17β-HSD type 2 mainly performs oxidation in human sebaceous glands, which may help protect against acne.

People with pemphigus are more likely to have conditions like hypothyroidism, inflammatory bowel disease, and diabetes.

Taking 5α-reductase inhibitors does not significantly increase the risk of breast cancer in men.

Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.