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Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Minoxidil boosts hair growth by activating PGHS-1.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Prostaglandin D₂ might be targeted for new male pattern baldness treatments.

New research on prostamide F2α has led to treatments for glaucoma and eyelash growth and may have more medical uses.

A compound from brown algae boosts the production of a certain inflammatory substance in skin cells.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

The PTGER2 gene is highly active in Cashmere goat skin and its activity changes with the hair growth cycle.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.

A substance called prostaglandin D2 is linked to stopping hair growth in men with common baldness.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Some treatments for autoimmune hair loss work, but JAK inhibitors like tofacitinib are promising for regrowth.

Finasteride may affect male fertility by interfering with specific sperm signaling.

Alopecia areata treatment should be personalized, using topical or systemic therapies based on severity, with promising options like JAK inhibitors needing more research.

Alopecia Areata has no cure, treatments are limited, and the condition often recurs, but new therapies like JAK inhibitors show promise.

Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.

Minoxidil 2% is more effective for female hair loss, but botanicals have fewer side effects.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

The document concludes that H2-antagonists and proton pump inhibitors are highly effective for ulcers, eradicating Helicobacter pylori is important to prevent recurrence, and misoprostol helps with NSAID-related ulcers.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.

Two children grew extra hair from taking omeprazole, which went away after they stopped the medication.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Alternative treatments show promise for hair growth beyond traditional methods.

Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.

Certain immune cells are more common on the top of the head and might help predict or treat common hair loss.