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    Glossary propylene glycol

    synthetic liquid that enhances skin absorption of active ingredients

    Propylene glycol is a synthetic liquid substance that absorbs water and is commonly used as a solvent in pharmaceuticals, including topical treatments for hair and skin conditions. It helps active ingredients penetrate the skin more effectively and is generally considered safe for use, though some individuals may experience skin irritation.

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    1. Relative Influence of Ethanol and Propylene Glycol Cosolvents on Deposition of Minoxidil into the Skin Journal of Pharmaceutical Sciences · 1994 · 34 citations
    2. Penetration of Minoxidil from Ethanol/Propylene Glycol Solutions: Effect of Application Volume and Occlusion Journal of Pharmaceutical Sciences · 1995 · 33 citations
    3. Experimental and computational approaches for measuring minoxidil solubility in propylene glycol + water mixtures at different temperatures Journal of Molecular Liquids · 2019 · 7 citations
    4. Skin deposition and permeation of finasteride<i>in vitro</i>: effects of propylene glycol, ethanol and sodium lauryl sulfate Pharmaceutical Development and Technology · 2014 · 5 citations
    5. ENHANCING THE PHYSICAL CHARACTERISTICS AND SHELF LIFE OF RICE WATER (ORYZA SATIVA L.) GEL SHAMPOO: THE ROLE OF PROPYLENE GLYCOL CONCENTRATION International Journal of Applied Pharmaceutics · 2024 · 1 citations
    6. Clinical Efficacy, Cosmetic Acceptability, and Local Tolerability of a New Formulation of Topical 5% Minoxidil without Propylene glycol: A 6-month, Multicentre, Real-life, Prospective, Assessor-Blinded Study in 196 Subjects with Hair Loss. The andldquo;NOMINALandrdquo; Trial Journal of clinical & experimental dermatology research · 2021
    7. The efficacy and safety of diphenylcyclopropenone solutions in propylene glycol and isopropanol. A comparative study of two formulas used for the treatment of 100 patients with alopecia areata Our Dermatology Online · 2017
    8. Efficacy and tolerance of 2,3-diphenylcyclopropenone in propylene glycol versus 2,3-diphenylcyclopropenone in isopropanol – a novel formula designed for the treatment of alopecia areata Nasza Dermatologia Online · 2017
    9. Efficacy, Tolerability, and Superiority of Propylene Glycol-Free, North American Witch-Hazel (Hamamelis virginiana)-Based Solution of 5% Minoxidil Sulfate for the Treatment of Female Androgenetic Alopecia International Journal of Trichology · 2023
    10. The “NOMINAL” trial: Clinical efficacy, cosmetic acceptability, and local tolerability of topical 5% minoxidil lotion without propylene glycol: A 6-month, multicentre, real-life, prospective, assessor-blinded study in 196 subjects with hair loss. Medical research archives · 2021
    11. New ethanol and propylene glycol free gel formulations containing a minoxidil-methyl-β-cyclodextrin complex as promising tools for alopecia treatment Drug Development and Industrial Pharmacy · 2014 · 18 citations
    12. Comparison of Topical Minoxidil 5% in Ethanol Plus Propylene Glycol Versus Minoxidil 5% in Ethanol Alone in Treatment of Women With Female Pattern Hair Loss Case medical research · 2019
    13. Formulasi Dan Uji Stabilitas Hair Tonic Kombinasi Ekstrak Daun Kelor (Moringa oleifera Lam.) Dan Madu Dengan Variasi Propilen Glikol Jurnal Multidisiplin Dehasen (MUDE) · 2026
    14. Penggunaan Simplex Lattice Design (SLD) dalam Optimasi HPMC dan Propilen Glikol Formula Gel Cinchonine Sebagai antibakteri Cutibacterium acnes (C.Acne) Healthy-Mu Journal · 2025
    15. Optimasi komposisi propilen glikol dan sorbital sebagai humectant dalam formula krim anti hair loss ekstrak saw palmetto [Serenoa repens] : aplikasi desain faktorial 2007
    16. Optimasi formula krim anti hair loss ekstrak saw palmetto [Serenoa repens] dengan propilen glikol dan gliserol sebagai humectant : aplikasi dengan faktorial 2007
    17. Allergic contact dermatitis to topical minoxidil solution: Etiology and treatment Journal of The American Academy of Dermatology · 2002 · 123 citations
    18. Topical Cyclosporine in Alopecia Areata Archives of Dermatology · 1987 · 69 citations
    19. Targeted gene delivery to skin cells in vivo: A comparative study of liposomes and polymers as delivery vehicles Journal of pharmaceutical sciences · 2002 · 68 citations
    20. Relative uptake of minoxidil into appendages and stratum corneum and permeation through human skin in vitro Journal of Pharmaceutical Sciences · 2009 · 55 citations
    21. Permeant lipophilicity and vehicle composition influence accumulation of dyes in hair follicles of human skin European journal of pharmaceutical sciences · 2003 · 44 citations
    22. In vitro skin permeation of monoolein nanoparticles containing hydroxypropyl β-cyclodextrin/minoxidil complex International Journal of Pharmaceutics · 2010 · 39 citations
    23. Positive lymphocyte transformation test in a patient with allergic contact dermatitis of the scalp after short-term use of topical minoxidil solution Contact Dermatitis · 2005 · 38 citations
    24. Contact dermatitis to Minoxidil Contact Dermatitis · 1985 · 34 citations
    25. Hair Follicle Targeting and Dermal Drug Delivery with Curcumin Drug Nanocrystals—Essential Influence of Excipients Nanomaterials · 2020 · 32 citations
    26. Allergic contact dermatitis from minoxidil Contact Dermatitis · 1995 · 32 citations
    27. Allergic contact dermatitis to Minoxidil Contact Dermatitis · 1985 · 29 citations
    28. Experimental and thermodynamic analyses of supercritical CO2-Solubility of minoxidil as an antihypertensive drug Fluid Phase Equilibria · 2020 · 28 citations
    29. Common Allergens Identified Based on Patch Test Results in Patients with Suspected Contact Dermatitis of the Scalp Skin appendage disorders · 2016 · 16 citations
    30. Pustular allergic contact dermatitis from topical minoxidil 5% 2007 · 16 citations